Functionalized manganese iron oxide nanoparticles: a dual potential magneto-chemotherapeutic cargo in a 3D breast cancer model

Phalake, Satish S.; Somvanshi, Sandeep B.; Tofail, Syed A. M.; Thorat, Nanasaheb D.; Khot, Vishwajeet M.

doi:10.1039/d3nr02816j

Cited by 44 publications

(3 citation statements)

References 40 publications

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“…In recent years, there has been significant progress in the development of core-shell NCs. Their excellent physical and chemical properties have attracted widespread interest in various fields, such as magnetic hyperthermia, catalysis, and EM functions [23][24][25]. In this study, we demonstrate the successful preparation of Co@Co 1−x S@C NCs through a sulfidation process using the precursor of Co@C NCs.…”

Section: Introductionmentioning

confidence: 78%

Enhanced interfacial polarization through the conversion of Co@C into Co@Co_1−xS@C nanocapsules utilizing a facile sulfidation process

Zhou,

Javid,

Saleem

et al. 2024

Phys. Scr.

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The design and development of efficient Co-based electromagnetic (EM) absorbents with double-shell structures have received relatively less attention in the literature. The construction of multiple heterointerfaces gives rise to a unique morphology that holds significant potential in expanding the absorbing frequency range. Co@Co1-xS@C nanocapsules (NCs) with Co as the cores, Co1-xSx and C as the middle and outside shells separately, were successfully prepared using a facile two step process: synthesizing Co@C core-shell NCs by arc-discharge method and subsequently converting them into Co@Co1-xS@C NCs through chemical sulfidation reaction. The experimental results indicate that the thickness of the carbon shell exhibits a decreasing trend (from 1 ± 0.1 nm to 0.6 ± 0.02 nm) following the post-sulfidation process, lasting for approximately two hours. The defect density of the carbon shell also declines from 1.88 ×1011 cm-2 to 1.14 ×1011 cm-2. The reduction in thickness of the carbon shell and the formation of new Co1-xS not only enable efficient manipulation of impedance matching between the dielectric shells and magnetic cores but also facilitate the construction of multiple interfacial polarizations. The study provides evidence that the multi-interfacial Co@Co1-xS@C nanocomposite serves as an effective EM absorbent achieving a minimum reflection loss (RL) up to –78.6 dB at a thickness of merely 1.52 mm within the frequency range of 2~18 GHz.

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Section: Introductionmentioning

confidence: 78%

Enhanced interfacial polarization through the conversion of Co@C into Co@Co_1−xS@C nanocapsules utilizing a facile sulfidation process

Zhou,

Javid,

Saleem

et al. 2024

Phys. Scr.

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“…142 Likewise, these magnetic nanoparticle platforms were further expanded for more than one functionalized targeting (e.g., for anticancer agents, like doxorubicin, and tumor-targeting aptamers, like AS1411) and for high magnetization structures using diisopropylamine (reducing agent with surface stabilization properties)-based polymeric magnetic nanocarriers as a promising theranostic modality against image-guided breast cancers. 143,144 Interestingly, in 2013, Burke et al developed nanoparticles (carbon nanotubes)-mediated localized PTT against "triple negative" (HER2, estrogen, and progesterone receptors) breast cancer stem cells (CD44 high /CD24 low ) that are recognized as the most difficult to treat. The beauty of this carbon nanotube (CNT) system is its efficient antenna behavior, i.e., absorbance under electromagnetic radiation and thermal conductance.…”

Section: Multimodal Nanoplatforms In Therapy Resistancementioning

confidence: 99%

“…, for anticancer agents, like doxorubicin, and tumor-targeting aptamers, like AS1411) and for high magnetization structures using diisopropylamine (reducing agent with surface stabilization properties)-based polymeric magnetic nanocarriers as a promising theranostic modality against image-guided breast cancers. 143,144…”

Section: Challenges Appended By Multimodal Nanotherapymentioning

confidence: 99%

Nanomedicine as a multimodal therapeutic paradigm against cancer: on the way forward in advancing precision therapy

Sandbhor,

Palkar,

Bhat

et al. 2024

Nanoscale

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Dielectric and Thermal Behavior of Al‐Doped Cobalt Titanate Nanoparticles

Bharathi,

Naidu,

Basha

et al. 2024

Cryst. Res. Technol.

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The AlxCo1‐xTiO3+δ (x = 0.2, 0.4, 0.6 & 0.8) (ACTO) nanoparticles are synthesized via hydrothermal method at low operating temperature of 423 K/8 h. The diiffraction patterns confirm the tetragonal phases of ACTO along with the secondary phases (*Co3O4). The morphology shows the homogeneous distribution of nanoparticles. In addition, for x = 0.2–0.4, a = b & c values are found to be decreasing from 0.3776 to 0.3771 nm & 0.8887–0.8878 nm, respectively, while for x = 0.6–0.8, the same values are found to be decreasing from 0.3780 to 0.3778 nm & 0.8881–0.8879 nm, respectively. The M–H curves provide the pure paramagnetic nature for x = 0.6 & 0.8 while the weak ferromagnetic nature for x = 0.2 & 0.4. At 8 MHz, the ɛ′ value of x = 0.2 (high cobalt content) shows the stabilized ɛ′ of ≈32.5 and the ɛ″ values of ACTO are changing from ≈1.6–10.6. Therefore, the x = 0.2 shows the high ɛ′ & ɛ″ suitable for high frequency dielectric absorber applications. The exponent “n” values determined using power law fit are noted to be increasing from 0.512 to 0.852 for x = 0.2–0.6 while the same is decreased to 0.664 for x = 0.8. All the “n” values are less than one and shows that the polaron hopping is slower than site relaxation. The mass loss, decomposition of various ingredient species, and other transition temperatures are evaluated by thermal study.

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Functionalized manganese iron oxide nanoparticles: a dual potential magneto-chemotherapeutic cargo in a 3D breast cancer model

Abstract: Localized heat generation from manganese iron oxide nanoparticles (MIONPs) conjugated with chemotherapeutics under the exposure of alternating magnetic field (magneto-chemotherapy) can revolutionize targeted breast cancer therapy. On the other hand,...

Cited by 44 publications

References 40 publications

Enhanced interfacial polarization through the conversion of Co@C into Co@Co_1−xS@C nanocapsules utilizing a facile sulfidation process

Enhanced interfacial polarization through the conversion of Co@C into Co@Co_1−xS@C nanocapsules utilizing a facile sulfidation process

Nanomedicine as a multimodal therapeutic paradigm against cancer: on the way forward in advancing precision therapy

Dielectric and Thermal Behavior of Al‐Doped Cobalt Titanate Nanoparticles

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Functionalized manganese iron oxide nanoparticles: a dual potential magneto-chemotherapeutic cargo in a 3D breast cancer model

Abstract: Localized heat generation from manganese iron oxide nanoparticles (MIONPs) conjugated with chemotherapeutics under the exposure of alternating magnetic field (magneto-chemotherapy) can revolutionize targeted breast cancer therapy. On the other hand,...

Cited by 44 publications

References 40 publications

Enhanced interfacial polarization through the conversion of Co@C into Co@Co1−xS@C nanocapsules utilizing a facile sulfidation process

Enhanced interfacial polarization through the conversion of Co@C into Co@Co1−xS@C nanocapsules utilizing a facile sulfidation process

Nanomedicine as a multimodal therapeutic paradigm against cancer: on the way forward in advancing precision therapy

Dielectric and Thermal Behavior of Al‐Doped Cobalt Titanate Nanoparticles

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Product

Resources

About

Enhanced interfacial polarization through the conversion of Co@C into Co@Co_1−xS@C nanocapsules utilizing a facile sulfidation process

Enhanced interfacial polarization through the conversion of Co@C into Co@Co_1−xS@C nanocapsules utilizing a facile sulfidation process