2009
DOI: 10.1590/s0001-37652009000300022
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Functionomics: the analysis of a postgenomic concept on the basis of pregenomic pharmacological studies in smooth muscle

Abstract: The term functionomics (Amin 2003, Neumann et al. 2004 refers to a postgenomic integrated Systems Biology (Attur et al. 2002) using a multidimensional approach for cells, tissues and organs. It considers current or future involvement among genomics, proteomics or metabolomics, including the main factors that cause biological responses and modulation under different conditions. Our objective in the present review is to summarize the contemporary understanding of functionomics of smooth muscle pharmacology, base… Show more

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