Functions of manganese in reproduction

Complexed amino acid minerals vs. bis-glycinate chelated minerals: Impact on the performance of old laying hens

“…This mineral is involved in the regulation of hormones such as estrogen and progesterone ( Assersohn et al., 2021 ; Park et al., 2004 ). Studies by Cao and Chen, (1987) demonstrated that Mn is involved in ovarian steroid synthesis in layers, as Mn serves as one of the cofactors in the biosynthesis of cholesterol compounds from enzymes, mevalonate kinase, and geranyl pyrophosphate synthetase ( Klimis Tavantzis et al., 1983 ; Studer et al., 2022 ). Leach and Gross (1983) reported that dietary Mn deficiency decreased egg production and eggshell thickness.…”

The Impact of Essential Trace Elements on Ovarian Response and Reproductive Outcomes following Single Euploid Embryo Transfer

“…Manganese is a cofactor of numerous enzymes, including some that modulate steroidogenesis, and acts as a component of antioxidant enzymes (e.g., manganese superoxide dismutase) [ 4 , 32 ]. Dietary manganese is present in green vegetables, nuts, cereals, and tea [ 4 ].…”

Manganese-based nanomaterials in diagnostics and chemodynamic therapy of cancers: new development

“…Such enzymes are instrumental in regulating metabolic activities including cholesterol synthesis, gluconeogenesis, and cartilage development. 18 The United States Food and Drug Administration (FDA) suggests the daily intake of manganese for adult males is 2.3 mg per day and for females 1.8 mg per day. 19 Leveraging its catalytic and redox capabilities, manganese modulates a spectrum of enzymes, including manganese superoxide dismutase (SOD), glutamine synthetase, and pyruvate carboxylase, among others.…”