Fundamental Study of DSA Images Using Gadolinium Contrast Agent(Originals)

Nagashima, Hiroyuki; Sakamoto, Hajime; Sano, Yoshitomo; Shiraishi, Akihisa; Igarashi, Hitoshi

doi:10.6009/jjrt.kj00003111387

Cited by 5 publications

(5 citation statements)

References 1 publication

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“…Also, contrast material should be injected for CTA and DSA that may be contraindicated for a number of patients where those undergoing MRA should be MRI compatible. 57,62,63 Removal of bony parts were used in several studies in the preprocessing step. It should be noted that without a sufficient model or human supervision, some calcified lesions may also be omitted, which leads to misdiagnosis.…”

Section: Discussionmentioning

confidence: 99%

Application of convolutional network models in detection of intracranial aneurysms: A systematic review and meta-analysis

et al. 2022

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Introduction Intracranial aneurysms have a high prevalence in human population. It also has a heavy burden of disease and high mortality rate in the case of rupture. Convolutional neural network(CNN) is a type of deep learning architecture which has been proven powerful to detect intracranial aneurysms. Methods Four databases were searched using artificial intelligence, intracranial aneurysms, and synonyms to find eligible studies. Articles which had applied CNN for detection of intracranial aneurisms were included in this review. Sensitivity and specificity of the models and human readers regarding modality, size, and location of aneurysms were sought to be extracted. Random model was the preferred model for analyses using CMA 2 to determine pooled sensitivity and specificity. Results Overall, 20 studies were used in this review. Deep learning models could detect intracranial aneurysms with a sensitivity of 90/6% (CI: 87/2–93/2%) and specificity of 94/6% (CI: 0/914–0/966). CTA was the most sensitive modality (92.0%(CI:85/2–95/8%)). Overall sensitivity of the models for aneurysms more than 3 mm was above 98% (98%-100%) and 74.6 for aneurysms less than 3 mm. With the aid of AI, the clinicians’ sensitivity increased to 12/8% and interrater agreement to 0/193. Conclusion CNN models had an acceptable sensitivity for detection of intracranial aneurysms, surpassing human readers in some fields. The logical approach for application of deep learning models would be its use as a highly capable assistant. In essence, deep learning models are a groundbreaking technology that can assist clinicians and allow them to diagnose intracranial aneurysms more accurately.

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Section: Discussionmentioning

confidence: 99%

Application of convolutional network models in detection of intracranial aneurysms: A systematic review and meta-analysis

et al. 2022

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“…The Food and Drug Administration (FDA) established the upper limit of the dose of Gd contrast medium for intravenous administration as 0.6 mL/kg. 5) A study indicated that the upper limit of the dose of Gd contrast medium to be administered into cerebral blood vessels was 65 mL. 6) In addition, another study performed the intra-arterial administration of Gd contrast medium at 1.7 mL/kg for endovascular embolism treatment in children with AVM, and reported that there were no complications, including renal dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Aneurysmal Coil Embolization Using Gadolinium in a Patient with Allergy to Iodinated Contrast Medium: Case Report

Uemura

Shimozato

Matsunaga

et al. 2018

JNET

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We report a patient with allergy to iodinated contrast medium for whom a working angle was prepared based on preoperative CTA data, and coil embolization was performed using gadolinium (Gd) contrast medium at minimum. Case Presentation: The patient was a 44-year-old female. For detailed examination of an unruptured cerebral aneurysm, contrast-enhanced CT was performed, leading to a diagnosis of an unruptured cerebral aneurysm, measuring 7 mm in maximum diameter, beside the left internal carotid artery. At this point, serious allergic symptoms were observed. Based on the CT data, we prepared a fluoroscopic image of the skull at a working angle on endovascular treatment. Under general anesthesia, body movement was restricted, and angiography with Gd contrast medium was performed by identifying the same angle of fluoroscopy as that on the above fluoroscopic image. Subsequently, coil embolization of the aneurysm was conducted using this image as a road map. Treatment was completed without complications. The volume of Gd contrast medium infused into the artery was 10 mL. Conclusion: The treatment of an unruptured cerebral aneurysm with a small volume of Gd contrast medium could be performed by adapting image processing from the preoperative CT data to fluoroscopy at the time of treatment.

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“…Problems associated with gadolinium are its low viscosity, the fact that the high speed of pulmonary arterial blood flow makes it difficult to view the blood flow with fluoroscopy, and that the technique is more difficult than when performed with iodine contrast. The effect of gadolinium contrast has also been reported to be approximately one fifth that of an iodine contrast [9] ; however, when an increased amount of gadolinium contrast medium is used, it can cause renal dysfunction. However, according to the guidelines for the use of gadolinium contrast for patients with renal failure, as recommended by the Japan Radiological Society and the Japan Society of Nephrology, there is insufficient evidence to support the claim that renal function of GFR ≥60 mL/min/1.73 m 2 increases the risk of nephrogenic systemic fibrosis (NSF).…”

Section: Discussionmentioning

confidence: 99%

Successful balloon pulmonary angioplasty with gadolinium contrast media for a patient with chronic thromboembolic pulmonary hypertension and iodine allergy

Nakamura

Ogo

Tsuji

et al. 2016

Respiratory Medicine Case Reports

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A 28-year-old male was referred to our hospital with dyspnea. He was diagnosed as having chronic thromboembolic pulmonary hypertension, and a pulmonary endarterectomy (PEA) was performed. However, exertional dyspnea remained because of residual pulmonary hypertension; therefore, the patient was re-admitted to our hospital 1 year after PEA. We performed computed tomography and pulmonary angiography and found web and band lesions in the distal pulmonary artery with a high pulmonary artery pressure. Although further management was complicated because the patient had an anaphylactic shock to iodine-based contrast media, we eventually completed five sessions of balloon pulmonary angioplasty (BPA) using gadolinium contrast medium. His symptoms and hemodynamics dramatically improved after a series of BPA. After 15 months, mean pulmonary arterial pressure reduced from 67 mmHg to 20 mmHg, and subjective symptoms improved from stage Ⅳ to I as per the WHO classification system. BPA is a potential procedure for residual pulmonary hypertension after PEA and could be safely performed using gadolinium contrast medium for patients with iodine allergy.

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Fundamental Study of DSA Images Using Gadolinium Contrast Agent(Originals)

Cited by 5 publications

References 1 publication

Application of convolutional network models in detection of intracranial aneurysms: A systematic review and meta-analysis

Application of convolutional network models in detection of intracranial aneurysms: A systematic review and meta-analysis

Aneurysmal Coil Embolization Using Gadolinium in a Patient with Allergy to Iodinated Contrast Medium: Case Report

Successful balloon pulmonary angioplasty with gadolinium contrast media for a patient with chronic thromboembolic pulmonary hypertension and iodine allergy

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