In many countries in the world, the conservation of habitats is at risk mainly due to anthropic pressures on the environment. A study was conducted to assess the extent to which sensitive and high nature-value habitats are damaged by high-impact human activities. Some evaluation methods that are applied may not be entirely appropriate to the characteristics of the investigated areas or may be very accurate but provide results that are delayed with respect to the occurrence of the events that created the loss of their characteristics. The main purpose of this study is to optimise some methodologies for monitoring the impacts of human activities making it possible to obtain better results in less time and with much lower costs. This methodology has been applied in two different areas present in the Puglia Region in south-eastern Italy, in the central Mediterranean area. The biotope fragmentation method was applied on coastal dunes, in the province of Brindisi, affected by an important tourist influx. The results of the inclusion, in the evaluation methodology, of the remote sensing of the paths indicate a more real situation on the state of fragmentation of the coastal dunes. The second methodology concerns the monitoring, through topographical profiles obtained from Sentinel-1 DEM images, of active and inactive mining sites, allowing to obtain of very detailed information on the progress of mining activities in a very short time. By implementing these methodologies, it is possible to improve the control of the territory allowing a more detailed analysis in order to safeguard the environment from impacting human activities and avoiding, as much as possible, the occurrence of illegal activities. Finally, compensation factors to ensure that human activities are conducted in a sustainable way are also evaluated.