Fundoplication for laryngopharyngeal reflux disease1

Westcott, Carl; Hopkins, Marbry B.; Bach, Kevin K.; Postma, Gregory N.; Belafsky, Peter C.; Koufman, James A.

doi:10.1016/j.jamcollsurg.2004.03.022

Cited by 64 publications

(54 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These symptoms include cough and hoarseness, which can be caused by extra-oesophageal reflux, but may also represent primary respiratory symptoms. This finding further supports the theory that these patients experience laryngopharyngeal reflux [13,27], which may precede microaspiration. It is unknown how the evolving changes in the lung transplant and BOS may affect extra-oesophageal reflux symptoms, but we believe improvements are possibly attributable to fundoplication.…”

Section: Discussionsupporting

confidence: 85%

“…The GIQLI questionnaire has been recommended by the European Association for Endoscopic Surgery for the assessment of quality of life after fundoplication [26]. The DeMeester reflux questionnaire is validated to assess reflux symptoms and the RSI has been validated in nontransplant patients as a marker of extra-oesophageal reflux [13], and has been used to assess the effects of fundoplication on extraoesophageal reflux [27,28].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life

Robertson¹,

Krishnan²,

Ward³

et al. 2011

Eur Respir J

View full text Add to dashboard Cite

Fundoplication may improve survival after lung transplantation. Little is known about the effects of fundoplication on quality of life in these patients. The aim of this study was to assess the safety of fundoplication in lung transplant recipients and its effects on quality of life.Between June 1, 2008 and December 31, 2010, a prospective study of lung transplant recipients undergoing fundoplication was undertaken. Quality of life was assessed before and after surgery. Body mass index (BMI) and pulmonary function were followed up.16 patients, mean¡SD age 38¡11.9 yrs, underwent laparoscopic Nissen fundoplication. There was no peri-operative mortality or major complications. Mean¡SD hospital stay was 2.6¡0.9 days. 15 out of 16 patients were satisfied with the results of surgery post fundoplication. There was a significant improvement in reflux symptom index and DeMeester questionnaires and gastrointestinal quality of life index scores at 6 months. Mean BMI decreased significantly after fundoplication (p50.01). Patients operated on for deteriorating lung function had a statistically significant decrease in the rate of lung function decline after fundoplication (p50.008).Laparoscopic fundoplication is safe in selected lung transplant recipients. Patient benefit is suggested by improved symptoms and satisfaction. This procedure is acceptable, improves quality of life and may reduce deterioration of lung function.

show abstract

Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life

Robertson¹,

Krishnan²,

Ward³

et al. 2011

Eur Respir J

View full text Add to dashboard Cite

show abstract

“…Short-and long-term results of open and laparoscopic antireflux surgery indicate beneficial results in 50-100 per cent of patients with extra-oesophageal symptoms 13 -20 . A study by Westcott et al 21 prospectively followed 44 patients with a diagnosis of laryngopharyngeal reflux for up to 14 months after laparoscopic Nissen fundoplication. Patients were evaluated by means of the reflux finding score, reflux symptom index and quality of life questionnaires before and after surgery.…”

Section: Discussionmentioning

confidence: 99%

“…A total of 41 patients completed the study, with improvement in 34. One of the reasons suggested for some of the patients failing to improve was exposure of the larynx to pH neutral reflux as PPIs do not eliminate retrograde fluid flow 21 .…”

Section: Discussionmentioning

confidence: 99%

Combined multichannel intraluminal impedance–pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication

Mainie

Tutuian

Agrawal

et al. 2006

British Journal of Surgery

258

139

View full text Add to dashboard Cite

show abstract

“…Westcott et al reported that there was an improvement in symptoms in 84 % of patients treated with fundoplication but that the surgical success rate was lower for patients with a weak PPI response before surgery [26]. Qadeer et al suggested that fundoplication performed on patients with suspected LPR, who did not respond to twice daily PPI treatment for 4 months, was not useful and that in those patients other laryngeal irritation factors such as allergies, sinusitis, and pulmonary pathologies should be considered [27].…”

Section: Discussionmentioning

confidence: 99%

The effect of antireflux surgery on laryngeal symptoms, findings and voice parameters

Şahin

Vardar

Ersin

et al. 2015

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

The aim of this study was to evaluate the effect of laparoscopic antireflux surgery (LARS) on the laryngeal symptoms, physical findings and voice parameters of gastroesophageal reflux disease (GERD) patients with or without laryngopharyngeal reflux (LPR). Forty-one GERD patients predominantly with LPR symptoms (Group I) and twenty-six GERD patients without LPR symptoms (Group II) who had LARS were prospectively analysed before and 2 years after the surgery. Upper gastrointestinal endoscopy, 24-h ambulatory pH or MII-pH monitoring was performed in all cases. A reflux study group including specialists from five departments in a university hospital decided surgical indications. Patients were asked to fill out a validated LPR and voice quality questionnaire (Reflux Symptom Index and Voice Handicap Index-10). Laryngeal findings were evaluated and scored using a laryngoscopic grading scale [Reflux Finding Score (RFS)], by four blinded ENT specialists. GRBAS scale was done by a blinded otolaryngologist. Voice parameters were measured objectively via the Multi Dimensional Voice Programme (MDVP). The mean age was 45.8 ± 8.5 for Group I (24 men) and 48.9 ± 12.3 for Group II (16 men). The mean follow-up after LARS was 24.5 ± 1.3 months for Group I and 25.2 ± 1.1 months for Group II. The preoperative mean score of RSI was 22.8 ± 7.4 vs. 11.2 ± 6.6; RFS was 10.6 ± 2.3 vs. 5.7 ± 2.5 and VHI was 18.07 ± 4.4 vs. 10.86 ± 3.3 for Group I and II, respectively. The postoperative mean score of RSI was 12.9 ± 6.4 vs. 8.4 ± 4.5; RFS was 6.9 ± 2.0 vs. 4.5 ± 2.3 and VHI was 9.59 ± 4.4 vs. 7.95 ± 3.5 for Group I and II, respectively. Group I had significantly lower RSI and RFS scores following LARS compared to the preoperative scores. LARS successfully improved RFS, RSI and VHI in carefully selected patients with GERD, especially the signs and symptoms related to the larynx and voice. Although the indications for LARS are limited in patients with LPR symptoms, these results favor the decision-making period of LARS.

show abstract

Fundoplication for laryngopharyngeal reflux disease1

Cited by 64 publications

References 32 publications

Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life

Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life

Combined multichannel intraluminal impedance–pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication

The effect of antireflux surgery on laryngeal symptoms, findings and voice parameters

Contact Info

Product

Resources

About