Fundus Autofluorescence Imaging Findings in Choroidal Osteoma

Autofluorescence of intraocular tumours

“…In a study of 74 eyes with choroidal osteoma by Shields et al [32], 10-year probability for tumour growth was 51%, tumour decalcification was 46%, related choroidal neovascularization was 31%, visual acuity loss of 3 or more Snellen lines was 45%, and poor visual acuity of 20/200 or worse was 56%. The autofluorescence of choroidal osteoma was described by Ascaso and Villén [33] as a hypoautofluorescence lesion with peripheral hyperautofluorescence associated with granular hypoautofluorescence dots. This pattern corresponds to an increased metabolic activity of the RPE along the margins of the tumour together with atrophic areas of RPE cell loss [33].…”

“…The autofluorescence of choroidal osteoma was described by Ascaso and Villén [33] as a hypoautofluorescence lesion with peripheral hyperautofluorescence associated with granular hypoautofluorescence dots. This pattern corresponds to an increased metabolic activity of the RPE along the margins of the tumour together with atrophic areas of RPE cell loss [33]. Navajas et al [34] reported a series of three patients with choroidal osteoma with relatively well preserved autofluorescence overlying the calcified tumour portion and general hypoautofluorescence in decalcified regions (Fig.…”

3D Reconstruction with Spiral Computed Tomography in Choroidal Osteoma

“…Fluorescein angiography usually shows diffuse patchy hyperfluorescence with late-phase generalized tissue staining. Optical coherence tomography demonstrates a highly reflective cavernous structure [1,2]. Orbital computed tomographic scan reveals a characteristic, well-defined, homogeneously radio-opaque plaque with the same density as bone at the level of the choroid.…”

“…It is usually unilateral and develops in the second or third decade of life, mostly in women [1,2]. Funduscopically, it is characterized by a well-demarcated, slightly elevated, yellow-white lesion located in the juxtapapillary or macular area.…”

De Novo Appearance of a Choroidal Osteoma in an Eye With Previous Branch Retinal Vein Occlusion

“…1 Fundus auto-fluorescence has also been described to assist in diagnosis. 14 Recently, optical coherence tomography (OCT) imaging is being used to determine the features of choroidal osteoma, and demonstrates a plate-like hyper-intense appearance, involving RPE atrophy, specifically at an early stage of the tumor’s evolution. 1 …”