Fungal Biofilms 2020

Rodrigues, Célia Fortuna; Romo, Jesús A.

doi:10.3390/jof7080603

Cited by 2 publications

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This form of growth, similar to bacterial biofilms, provides them with more nutrients, metabolic cooperation, defense, and the exchange of many unique capabilities. This form also makes them much more resistant to antifungal therapy than planktonic forms [ 12 , 13 ]. Biofilm as a structure plays a crucial role in survival in unfavorable conditions of the external environment; however, when it also forms on the surface of human body (implant surface), it can cause serious infections, even leading to death.…”

Section: Biofilmmentioning

confidence: 99%

Modern Microbiological Methods to Detect Biofilm Formation in Orthopedy and Suggestions for Antibiotic Therapy, with Particular Emphasis on Prosthetic Joint Infection (PJI)

Mikziński,

Kraus,

Widelski

et al. 2024

Microorganisms

View full text Add to dashboard Cite

Biofilm formation is a serious problem that relatively often causes complications in orthopedic surgery. Biofilm-forming pathogens invade implanted foreign bodies and surrounding tissues. Such a condition, if not limited at the appropriate time, often requires reoperation. This can be partially prevented by selecting an appropriate prosthesis material that prevents the development of biofilm. There are many modern techniques available to detect the formed biofilm. By applying them we can identify and visualize biofilm-forming microorganisms. The most common etiological factors associated with biofilms in orthopedics are: Staphylococcus aureus, coagulase-negative Staphylococci (CoNS), and Enterococcus spp., whereas Gram-negative bacilli and Candida spp. also deserve attention. It seems crucial, for therapeutic success, to eradicate the microorganisms able to form biofilm after the implantation of endoprostheses. Planning the effective targeted antimicrobial treatment of postoperative infections requires accurate identification of the microorganism responsible for the complications of the procedure. The modern microbiological testing techniques described in this article show the diagnostic options that can be followed to enable the implementation of effective treatment.

show abstract

Section: Biofilmmentioning

confidence: 99%