Fungal, Mycobacterial, and Nocardia infections and the eye: an update

Garg, Prashant

doi:10.1038/eye.2011.332

Cited by 77 publications

(68 citation statements)

References 50 publications

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“…Of those eyes correctly diagnosed, almost 50% lost functional vision. In the vast majority of cases, infectious scleritis follows accidental or surgical trauma, and rarely can be attributed to hematogenous spread [2,3,4,5]. We describe a patient with delayed diagnosis of Fusarium scleritis who had no clear identifiable source for her infection.…”

Section: Introductionmentioning

confidence: 99%

Occult Fungal Scleritis

et al. 2016

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Purpose: To heighten awareness of occult fungal scleritis. Method: Case report and review of the literature. Results: A 73-year-old woman with diabetes mellitus was diagnosed for 3 months with immune-mediated scleritis and subsequently treated with corticosteroids. On referral, the patient had a scleral nodule with contiguous corneal infiltrate and hypopyon. Culture grew Fusarium species not further classified. The infection could not be controlled with antifungal therapy, and the eye was removed. No exogenous or endogenous source for the infection could be identified by clinical history or examination. Conclusion: Fungal scleritis can develop in persons without a history of foreign body injury, minor trauma, or evidence of endogenous fungemia. A high index of suspicion for infectious scleritis must be maintained in persons with presumed immune-mediated scleritis who fail to respond to conventional therapy, particularly if they present with decreased visual acuity.

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Section: Introductionmentioning

confidence: 99%

Occult Fungal Scleritis

et al. 2016

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“…are often resistant to these regimens and alternative antimicrobials have emerging roles for NTMs infection due to the potency, pharmacokinetic property, and safety. Especially among rapidly growing NTM, a combination of aminoglycosides, fluoroquinolones and macrolides has shown successful outcome [3,8,10]. On the other hand, slow growers are more sensitive to anti-tuberculosis drugs [4].…”

Section: Discussionmentioning

confidence: 99%

“…Since then, the infections have been increasingly reported in a variety of ocular infections range from periocular, conjunctival, scleral, corneal, orbital and intraocular infections [1,3,4]. Rapid growers especially M. chelonae, M. fortuitum and M. abscessus are the most common causes of ocular infections and generally associated with poor visual outcomes [4][5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Nontuberculous Mycobacterial Endophthalmitis: Case Series and Review Literature

Pinitpuwadol

Tesavibul

Boonsophon

et al. 2020

Preprint

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“…Various methods include pretreatment techniques in combination with enrichment techniques and selective antimicrobial agents have been developed to isolation the actinomycetes genera from natural habitats [22]. Nocardia can grow on routine bacterial, fungal, or mycobacterial culture media [23]. Few studies have been carried out in the isolation of Nocardia from soil using various methods.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Various Methods for Isolation of Nocardia from Soil

Rasoulinasab

Fatahi-Bafghi

Habibnia

et al. 2017

Zahedan J Res Med Sci

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Background: The genus Nocardia is Gram-positive, aerobic filamentous bacilli and saprophytic micro-organisms that can be isolated from freshwater, salt water, dust and decaying vegetation especially the soil. This study aimed to investigate the several media for to determine a suitable culture media with the ability to better for the isolation of Nocardia from soil. Methods:In this study, 400 soil samples were collected from different areas from Iran. The soil samples were then cultured on the four culture media such as Humic acid vitamin B agar, Paraffin agar, Sabouraud dextrose agar supplemented whit cycloheximide and carbon-free broth containing paraffin rods and incubated at 35°C. All of culture media investigated every 3 days for a month. Colonies suspicious to Nocardia were stained with Gram-stain, acid-fast and partially acid-fast and evaluated for resistance to lysozyme.Results: From 400 soil samples, the number of 62, 10, 28 and 19 strains of Nocardia were isolated by paraffin rods, Humic Acid Vitamin B agar, Paraffin agar and Sabouraud dextrose agar whit cycloheximide, respectively. Most Nocardia strains were isolated using paraffin bait technique. Conclusions:Isolation of Nocardia spp. is enhanced by using the paraffin baiting technique that relies on the selective ability of this micro-organism to metabolize paraffin.

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Fungal, Mycobacterial, and Nocardia infections and the eye: an update

Cited by 77 publications

References 50 publications

Occult Fungal Scleritis

Occult Fungal Scleritis

Nontuberculous Mycobacterial Endophthalmitis: Case Series and Review Literature

Comparison of Various Methods for Isolation of Nocardia from Soil

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