Fungal Mycotic Aneurysm in a Case of Acute Lymphoblastic Leukemia

Sahu, Kamal Kant; Yanamandra, Uday; Dhawan, Rishi; Khadwal, Alka; Dhandapani, Sivashanmugam; Malhotra, Pankaj

doi:10.1007/s12288-015-0574-6

Cited by 5 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 Risk factors are: arterial injury, history of infections, immunosuppressed status, and atherosclerosis in the elderly. 3 Our patient had recurrent Gram-negative bacteremia, immunosuppression due to his underlying disease (AML), and chemotherapy.…”

Section: Discussion-conclusionmentioning

confidence: 93%

Mycotic Pulmonary Aneurysm Managed With Covered Stent

Alquichire-Luna

García-Bohórquez

Hernández-Vargas

et al. 2021

Vasc Endovascular Surg

View full text Add to dashboard Cite

Mycotic aneurysms are vascular dilations caused by fungal or bacterial infections. The involvement of the pulmonary artery or its branches is extremely rare with only a few cases reported in the literature posing a diagnostic challenge. We present the case of a young adult patient with acute myeloid leukemia undergoing chemotherapy, who presented with febrile neutropenia, recurrent bacteremia due to Pseudomona Aeruginosa and Klebsiella Pneumonie and hemoptysis. The management was unconventional, opting for the placement of a covered endovascular stent, being the first successful case with this reported technique. Rapid detection of this pathology and individualization in the management of each patient is essential because of high risk of mortality due to sepsis and rupture of the aneurysm.

show abstract

Section: Discussion-conclusionmentioning

confidence: 93%

Mycotic Pulmonary Aneurysm Managed With Covered Stent

Alquichire-Luna

García-Bohórquez

Hernández-Vargas

et al. 2021

Vasc Endovascular Surg

View full text Add to dashboard Cite

show abstract

“…[ 19 ] Immunocompromised statuses such as HIV, tuberculosis, cancers, and diabetes increase the susceptibility to variety of the unusual microbes which are difficult to diagnose and treat. [ 20 21 22 23 24 ]…”

Section: Discussionmentioning

confidence: 99%

Aerococcus-Related Infections and their Significance

Sahu

Lal

Mishra

et al. 2021

Journal of Microscopy and Ultrastructure

View full text Add to dashboard Cite

Introduction: Aerococcus spp. is a Gram-positive, catalase- and oxidase-negative, microaerophilic, nonmotile bacteria species rarely associated with human infections such as arthritis, bacteremia, endocarditis, and meningitis. The bacteria are also often confused with streptococci species or treated as a contaminant. Patients and Methodology: We conducted a retrospective, observational cohort study on all patients with Aerococcus spp. isolates in blood samples from July 2010 to June 2019. All categorical data were presented as counts and proportions, whereas continuous data were presented as median and interquartile ranges. Results: A total of 20 Aerococcus spp. isolates were identified over the study period of 9 years. Of these, Aerococcus urinae was isolated in 10 (50%), Aerococcus viridans in 6 (30%), and Aerococcus spp. (not speciated) in 4 (20%). The median age was 74.3 years (12 males and 8 females). The two most frequent presentations were fever (15 of 20) and altered mentation (6 of 15). Most of the patients (11 of 15) had at least one predisposing comorbidity related to the urinary tract system (8 with recurrent urinary tract infection, 7 with urinary incontinence, 3 with an indwelling catheter, 2 with renal stones, and 1 each with benign prostatic hyperplasia and a recent cystoscopy). The median white blood cell count was 18,426 cells/mL, median hemoglobin 10.96 g/dL, median platelet count 191,000 cells/μL, median blood urea nitrogen 28.6 mg/dL, and median creatinine 1.54 mg/dL. The urinary tract was the most likely source of bacteremia (10 of 20) based on either imaging findings (5 cases), positive urine culture for Aerococcus spp. (4 cases), or instrumentation history (1 case). In the rest, the cause of bacteremia could not be found. Endocarditis was suspected in 9 out of 20 patients. Transthoracic echocardiography/transesophageal echocardiography (TEE) confirmed 3 cases (2 aortic valves, 1 mitral valve and pacemaker). Interestingly, one case had septic emboli causing a right frontal stroke with a normal TEE and normal Doppler study for deep venous thrombosis. Blood cultures were positive in 35% (7 of 20) with polymicrobial growth, 3 with coagulase-negative staphylococci, 2 with Enterococcus faecalis , and the other 2 each with Diphtheroids spp. and Proteus mirabilis. Of the 20 cases, 9 and 10 required intensive care unit level care and vasopressor support, respectively. Most of the patients were treated for 5–14 days except the 3 cases with infective endocarditis (IE). The median hospital stay duration was 6.55 days with 2 fatalities (2 out of 20 patients). Conclusion: Old age and underlying urologic conditions are the best-known risk factors f...

show abstract