Fungal periapical abscess and the burn patient: A report of two cases of an unreported source for systemic infection

Serio, Stephen; Burgess, Brian; Voigt, David W.

doi:10.1016/j.burns.2017.05.003

Cited by 1 publication

(8 citation statements)

References 18 publications

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“…Among them, 28 case series and 15 irrelevant studies were excluded. Finally, 36 case reports encompassing 44 burn patients were included for the final analysis 10–45 …”

Section: Resultsmentioning

confidence: 99%

“…In 36 of the 44 cases, fungal infections were initially suspected and identified from the burn wound samples 10–27,31–33,35–37,39–45 . In the remaining 8 cases, presentations of fungal wound infection were not observed, whereas invasive fungal infections were found in other sites such as blood, arterial thrombosis, teeth, feces, urine, sputum, and tracheal fluid 28–30,34,38 …”

Section: Resultsmentioning

confidence: 99%

“…In both cases, cultures of blood, urine, or sputum failed to reveal a source for infection. Although cultures of teeth revealed fungal infection with Candida species 30 . Fortunately, all those cases were finally cured with proper antifungal therapies and other interventions.…”

Section: Discussionmentioning

confidence: 96%

“…Above-knee amputation was performed, and infection of Aspergillus flavus of the lower extremity associated with acute thrombosis was identified 34 . Serio et al 30 reported 2 cases of fungal periapical abscess in burns. In both cases, cultures of blood, urine, or sputum failed to reveal a source for infection.…”

Section: Discussionmentioning

confidence: 99%

“…Finally, 36 case reports encompassing 44 burn patients were included for the final analysis. Of the 44 cases, 18 cases originated from the United States 10,12,13,16,18,22,23,30,31,[33][34][35]38,39,43,45 ; 18 cases originated from 5 Asian countries, including China, 17,20,29 Korea, 15 India, 36,[40][41][42] Iran, 26,39 and Vietnam 11,32 ; and the remaining 8 cases originated from France, 14 Australia, 19 Poland, 21 Jamaica, 24 German, 27 Switzerland, 25 Portugal, 28 and the Czech Republic, 44 respectively. The cases consisted of 31 males, 11 females, and 2 nonspecific sex identities.…”

Section: Literature Searchmentioning

confidence: 99%

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Fungal Infection in Burn Patents

Lineaweaver

Breland

2021

Ann Plast Surg

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Objectives The aims of this study were to review recent fungal infection case reports published, evaluate the treatment regimens and clinical outcomes, and provide recommendations for future management. Methods A review of case reports published over the last decade was conducted. PubMed was searched to collect the relevant citations using a combination of the key words (“burn,” “burned,” “burns,” “fungal,” “fungi,” and “fungus”) in title or abstract. Case series, reviews, guidelines, and experimental and non-English studies were excluded. Statistical analyses were performed using Microsoft Excel 2019. Results A total of 36 case reports encompassing a total of 44 burn patients with fungal infection were included in the final analysis. Ablative surgeries, including surgical excision, debridement, skin graft, vitrectomy, teeth extraction, valve replacement, or amputation, were performed in 38 cases after the suspicion or identification of fungal infection. Twenty-nine of them were eventually discharged, yielding a survival rate of 76.3%. In the remaining 6 cases, ablative surgery was not mentioned and 3 of them eventually died, yielding a survival rate of 50%. The total mortality was 27.27%. Among the 12 death cases, 1 was infected with Candida albicans, 1 with non-albicans Candida, 2 with Aspergillus spp, 2 with Fusarium spp, 4 with Zygomycetes, and 2 with other fungal species. Conclusions The overall mortality of fungal wound infection is still high in burn patients around the world, especially those infected with non-Candida species. Early diagnosis of fungal infection, early initiation of appropriate antifungal therapy, and effective surgical intervention are key measures to improve the treatment effect and reduce the mortality of fungal infection in burn patients.

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“…Among them, 28 case series and 15 irrelevant studies were excluded. Finally, 36 case reports encompassing 44 burn patients were included for the final analysis 10–45 …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%