1983
DOI: 10.7326/0003-4819-99-3-334
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Fungal Peritonitis in Patients on Continuous Ambulatory Peritoneal Dialysis

Abstract: Fungal peritonitis is a rare complication in patients on continuous ambulatory peritoneal dialysis. We report five recent cases and their management. The fungi isolated were Candida albicans, C. parapsilosis, Exophiala jeanselmei, Drechslera spicifera, and a Fusarium species. Chemotherapy was attempted with various regimens including oral ketoconazole, intravenous or intraperitoneal amphotericin B, and oral flucytosine. Pharmacokinetic studies were done in two patients receiving treatment with one of these dru… Show more

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Cited by 210 publications
(105 citation statements)
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“…Both long-term PD therapy and infection play roles in the development of EPS in the PD patient. Fungal infections cause severe infectious peritonitis related to PD therapy, although they are not common (33). Peritoneal fungal infection provokes consideration of withdrawal of PD therapy in the patient according to recent guidelines (5), because of the poor prognosis and risk of development of EPS.…”
Section: Discussionmentioning
confidence: 99%
“…Both long-term PD therapy and infection play roles in the development of EPS in the PD patient. Fungal infections cause severe infectious peritonitis related to PD therapy, although they are not common (33). Peritoneal fungal infection provokes consideration of withdrawal of PD therapy in the patient according to recent guidelines (5), because of the poor prognosis and risk of development of EPS.…”
Section: Discussionmentioning
confidence: 99%
“…Less frequently, the infection may occur as a result of skin breakdown, such as burns and wounds (74), or the presence of foreign bodies, such as keratitis in contact lens wearers (23), which at times causes outbreaks of fusarial keratitis (16). Peritonitis in patients receiving continuous ambulatory peritoneal dialysis has also been described (34,52,92). Other infections in immunocompetent patients include sinusitis (56), pneumonia (62,97), thrombophlebitis (69), fungemia with or without organ involvement (74,104), endophtalmitis (35,86), septic arthritis (51), and osteomyelitis (10).…”
Section: Epidemiology and Clinical Spectrum Of Fusariosismentioning
confidence: 99%
“…Peritonitis occurs essentially only in patients receiving peritoneal dialysis (6,8,69,97,106,115,117,144,197,261,302,305,367,405,416,461,466,563,598,605,618,619,656,690,762,765,783,784). The presentation is usually subacute, with many patients being without significant symptoms.…”
Section: Phaeohyphomycosismentioning
confidence: 99%