Fungicide Selective for Basidiomycetes

Abstract

Concentrations of 2,3-dihydro-5-carboxanilido-6-methyl-1,4-oxathiin lower than 8 parts per million prevented mycelial growth of a number of Basidiomycetes. By contrast, mycelial growth of various other fungi-Phycomycetes, Ascomycetes, and Deuteromycetes-was 50 percent inhibited only by concentrations of 32 ppm or higher. Two exceptions to this pattern of selective fungitoxicity were found:an isolate of Rhizoctonia solani was not as sensitive as other Basidiomycetes, and the deuteromycete Verticillium alboatrum was inhibited by lower concentrations than affected other fungi in this group. Spore germination of two Basidiomycetes, Uromyces phaseoli and Ustilago nuda, was inhibited 95 percent or more at 10 ppm.

Identification of three mutant loci conferring carboxin-resistance and development of a novel transformation system in Aspergillus oryzae

“…Carboxin is a systemic fungicide that is highly effective against basidiomycete fungi (Edgington et al, 1966). Carboxin prevents mitochondrial respiration by inhibiting the activity of mitochondrial respiratory Complex II, which is also referred to as succinate:ubiquinone reductase (SQR) or succinate dehydrogenase (SDH) (Ulrich and Mathre, 1972).…”

Synthesis And Fungicidal Activity of N,S- Substituted α-Thio-β-aminocrotonanilides

“…However, in in vitro tests these compounds did not control Alternaria solani, Fusarium oxysporum, Pythium Spp., or Rhizoctonia solani at 500 p.p.m. This is in contrast to Vitavax which gives excellent control of most basidiomycetes such as Rhizoctonia solani and is also active on the other fungal species (8). In addition in vioo greenhouse tests on tomato early blight and powdery mildew on beans at 500 p.p.m.…”

The development of synthetic fungicides; trends and prospects

“…The compound 2,3-dihydro-5-carboxyanilido-6-methyl-l,4-oxathiin, reported by Edgington et al (1966) ("Vitavax"). The compound 2,3-dihydro-5-carboxyanilido-6-methyl-l,4-oxathiin, reported by Edgington et al (1966) ("Vitavax").…”

“…II 0 2,3-dihydro-5-carboxyanilido-6-methyl-l,4-oxathiin (Edgington et al, 1966) N ~/ %/C--NH--COOCH3…”