Fusarium wilt is a significant disease of vegetables that affects the tomato crop and significantly reduces productivity and is the most severe, and worldwide terrible disease. Classified on morphological criteria, pigmentation on PDA, sporulation and spore shape, the pathogenic fungus isolated from the infected tomato plant in the current investigation was identified as Fusarium oxysporum F. sp. lycopersici. Five extracts of the plant species Zingibire officinale, Melia azedarach, Nerium oleander, Ocimum basilicum and Allium sativum were tested in vitro for their fungitoxicity against the pathogen under consideration using the poisoned food technique with different concentrations (20,40,60 and 80%). The purpose of this research is to provide a safe alternative to synthetic fungicides, in comparison to the control, all of the phytoconstituents evaluated substantially decreased pathogen mycelial formation. Nevertheless, among the five plant extracts that were determined Allium sativum was significantly superior over other treatments and recorded (95.85%), Ocimum basilicum (93.15%), Nerium oleander (92.89%) followed by Melia azedarach, Zingibire officinale recorded (55%), (43%) separately.