Furanocoumarins as Phytoalexines in<i>Angelica</i>Roots Stressed by Fungi

Głowniak, Kazimierz; Gawron, Antoni; Dragan, T.

doi:10.1055/s-2006-960409

Cited by 1 publication

(1 citation statement)

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“…Their inhibitory effect on HIV replication has also been ascertained [6]. Some of the coumarins are important in plant defence mechanisms and their presence on the surface cuticle acts as a barrier against bacteria, fungi, small insects, and UV radiation [7,8], although some of the furanocoumarins are potent photosensitizers when activated by near-UV light [9].…”

Section: Introductionmentioning

confidence: 99%

Computer-assisted searching for coumarins inPeucedanum alsaticumL. andPeucedanum cervaria(L.) Lap.

Skalicka-Woźniak¹,

Markowski²,

Świeboda³

et al. 2009

Acta Chromatographica

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This work is dedicated to Professor Edward Soczewiński on the occasion of his 80th birthdaySummary. The objective of the work was continuation of our study on identification of target coumarins in extracts from Peucedanum alsaticum L. and Peucedanum cervaria (L.) Lap., by use of ChromSword, on the basis of relationships between retention data and descriptors such as partial molecular volume of structural fragments in water and energies of electrostatic interactions of bond dipoles with water (QSRR). The coumarins were mainly identified by comparing UV spectra from gradient runs with spectra from the literature. The presence of columbianadin, ostruthin, and 8methoxypeucedanin in the fruits of P. cervaria (L.) Lap. and oxypeucedanin and isoimperatorin in the fruits of P. alsaticum was confirmed. The optimum conditions obtained from DryLab simulation were used for both RP-HPLC and RP-UPLC.

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