In this issue of JAMA, the United States Preventive Services Task Force (USPSTF) recommends that clinicians refer pregnant and postpartum (ie, perinatal) persons who are at increased risk for depression to counseling interventions (B recommendation). 1 Based on a systematic review of 50 studies, 2 the USPSTF "concludes with moderate certainty that providing or referring pregnant or postpartum women at increased risk to counseling interventions has a moderate net benefit in preventing perinatal depression." 1 Women have frequent contact with clinicians during the perinatal period, rendering this a particularly opportune time to identify and treat those at risk for depression. Furthermore, perinatal women may be highly motivated to engage in behaviors that promote both their own and their infants' well-being. The most important take-home message from the USPSTF recommendation is that perinatal depression is preventable.
Burden of Perinatal DepressionApproximately 14% of perinatal women experience depression, making it one of the most common complications of childbirth. 3 The adverse correlates and consequences of perinatal depression are well established and include increased risk of preterm birth, less positive and more negative parenting behaviors, emotional and behavioral problems among offspring, and higher health care costs. 4 Treating women at risk for perinatal depression may avert the long reach of negative consequences on maternal and child health and well-being.