Further examination of the relationship between anxiety sensitivity and depression: The mediating role of experiential avoidance and difficulties engaging in goal-directed behavior when distressed

Tull, Matthew T.; Gratz, Kim L.

doi:10.1016/j.janxdis.2007.03.005

Cited by 133 publications

(83 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These data are consistent to our predictions and provide evidence for the theoretical suggestion that attempts at control over unwanted private events, are not seen as a practical means for improving life functioning (McCracken & Eccleston, 2006;Tull & Gratz, 2008). These data are also in accordance to previous studies that have also suggested the importance of experiential avoidance as a signifi cant predictor of patient function even when tested within a wider model that included other strong predictors such as pain and pain acceptance (McCracken & Zhao-O'Brien, 2010).…”

Section: Discussionsupporting

confidence: 92%

The mediation effect of experiential avoidance between coping and psychopathology in chronic pain

Costa¹,

Pinto‐Gouveia²

2011

Clin Psychology and Psychoth

View full text Add to dashboard Cite

This study explores experiential avoidance as a mediator in the relationship between coping (rational coping, avoidant coping and detached/ emotional coping) and psychopathology (depression, anxiety and stress). A battery of self-report questionnaires was used to assess coping, experiential avoidance and depression, anxiety and stress in 70 participants with a chronic pain from Portuguese primary health care units. Regression analyses were performed and showed preliminary evidence supporting the mediation role of experiential avoidance in a Portuguese sample with chronic pain. Results show that experiential avoidance partially or fully mediate the effects of rational coping and detached/emotional coping on depression and stress. Implications for clinical practice were discussed and suggest that psychopathology is not necessary direct product of coping and other processes, such as experiential avoidance, are likely involved.

show abstract

Section: Discussionsupporting

confidence: 92%

The mediation effect of experiential avoidance between coping and psychopathology in chronic pain

Costa¹,

Pinto‐Gouveia²

2011

Clin Psychology and Psychoth

View full text Add to dashboard Cite

show abstract

“…Consistent with the above conceptualizations, studies in the adult literature find EA and AS are significantly related yet distinct constructs Kampfe et al 2012;Pickett et al 2012). Research on adults has found both EA and AS to be related to depression and anxiety Kampfe et al 2012;Tull and Gratz 2008). For example, in undergraduate students AS was related to depression after controlling for anxiety, and EA was significantly related to depression after controlling for both anxiety and AS (Tull and Gratz 2008).…”

Section: Relations Between Experiential Avoidance and Anxiety Sensitimentioning

confidence: 83%

Experiential Avoidance and Anxiety Sensitivity: Independent and Specific Associations with Children’s Depression, Anxiety, and Social Anxiety Symptoms

Epkins

2015

J Psychopathol Behav Assess

View full text Add to dashboard Cite

Experiential avoidance (EA) is a key component in acceptance and commitment therapy (ACT) theory and research. EA is associated with a wide range of psychopathology in adults including anxiety, in particular social anxiety, and depression, yet little research exists on EA in youth. Anxiety sensitivity (AS), like EA, has been viewed as a form of distress tolerance or emotion regulation. In a sample of 124 children (age 10 to 12), this study examined the independent and specific relations of EA and AS to children's depression, anxiety, and social anxiety symptoms, both before and after controlling for comorbid symptoms. EA and AS had independent associations with each of children's depression, anxiety, and social anxiety; and EA had significantly stronger relations than AS with each of children's social anxiety and anxiety. After controlling for depression, only EA (and not AS) was uniquely related to both children's anxiety and social anxiety. After controlling for anxiety and social anxiety, only AS (and not EA) was uniquely related to depression. After controlling for depression and social anxiety, neither EA nor AS was significantly related to anxiety. In contrast, after controlling for depression and anxiety, EA (and not AS) showed a significant and unique relation to children's social anxiety. These findings indicate: 1) there are distinctions between EA and AS; 2) EA and AS are overlapping yet independent correlates for each of depression, anxiety and social and anxiety; and 3) EA and AS show some differential relations with children's depression, anxiety, and social anxiety when comorbid symptoms are considered. Theoretical and treatment implications are highlighted.

show abstract

“…One possible explanation for this is that S′/S′ genotypes might have a pre-clinical baseline disposition to avoid negative information to counteract heightened amygdala responsivity to negative information Heinz et al 2005;Pezawas et al 2005). In support of this theory, avoidance behavior is generally recognized as a mediating factor in anxiety disorders and in the onset of depression (Tull and Gratz 2008). Another possible explanation might be that S′/S′ genotypes spend more time on the elaboration of negative material which might increase their vulnerability to depression.…”

Section: Discussionmentioning

confidence: 98%

Differential effects of 5-HTTLPR genotypes on mood, memory, and attention bias following acute tryptophan depletion and stress exposure

Firk

Markus

2008

Psychopharmacology

View full text Add to dashboard Cite

Rationale Polymorphisms of the serotonin transporter gene (5-HTTLPR) may be associated with increased vulnerability to acute tryptophan depletion (ATD) and depression vulnerability especially following stressful life events. Objective The aim of the present study was to investigate the effects of ATD in subjects with different 5-HTTLPR profiles before and after stress exposure on affective and cognitive-attentional changes. Materials and methods Eighteen subjects with homozygotic short alleles (S′/S′) and 17 subjects with homozygotic long alleles (L′/L′) of the 5-HTTLPR participated in a double-blind, placebo-controlled, crossover design to measure the effects of ATD on mood, memory, and attention before and after acute stress exposure. Results ATD lowered mood in all subjects independent of genotype. In S′/S′ genotypes, mild acute stress increased depressive mood and in L′/L′ genotypes increased feelings of vigor. Furthermore, S′/S′ genotypes differed from L′/L′ genotypes on measures of attention independent of treatment and memory following ATD. Conclusions Polymorphisms of the 5-HTTLPR differentially affect responses to mild stress and ATD, suggesting greater vulnerability of S′/S′ carriers to serotonergic manipulations and supporting increased depression vulnerability.

show abstract

Further examination of the relationship between anxiety sensitivity and depression: The mediating role of experiential avoidance and difficulties engaging in goal-directed behavior when distressed

Cited by 133 publications

References 49 publications

The mediation effect of experiential avoidance between coping and psychopathology in chronic pain

The mediation effect of experiential avoidance between coping and psychopathology in chronic pain

Experiential Avoidance and Anxiety Sensitivity: Independent and Specific Associations with Children’s Depression, Anxiety, and Social Anxiety Symptoms

Differential effects of 5-HTTLPR genotypes on mood, memory, and attention bias following acute tryptophan depletion and stress exposure

Contact Info

Product

Resources

About