Further Experiences with an Operation for Thecure of Peyronie’S Disease

Lowsley, Oswald S.; Boyce, William H.

doi:10.1016/s0022-5347(17)68843-8

Cited by 84 publications

(24 citation statements)

References 5 publications

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“…The use of grafts for correcting Peyronie's disease was first described in 1950, 13 and since then, many materials and different techniques have been proposed with variable results 3, 14, 15, 16, 17. Our present work is not about the material for grafting, but it focused on the technique of opening the corpora cavernosa, which enabled graft area reduction and avoided geometric and mechanical abnormalities.…”

Section: Discussionmentioning

confidence: 98%

Practical Computerized Solution for Incision and Grafting in Peyronie's Disease

Miranda

Sampaio

2016

Sexual Medicine

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IntroductionPenile curvature correction with plaque incision and graft (PIG) increases the risk of erectile dysfunction (ED) and is associated with mechanical and geometric abnormalities.AimsThe aim of this study was to create and validate a new PIG technique using minimum graft area to correct simple or complex penile curvature with or without hourglass deformity, while avoiding mechanical and geometric abnormalities.MethodsUsing our cotton fabric model, we created a mathematic solution for PIG with no residual defects. This was applied in nine men who had sufficient penile rigidity while penetrating their respective partners. They underwent fascia lata patch corporoplasty using the new developed technique (iPad [Apple Corp, Palo Alto, CA, USA] app: iGrafter). Subjects answered the 5-item version of the International Index of Erectile Function (IIEF-5) questionnaire preoperatively and at the end of follow-up.Main Outcome MeasuresThe main outcome measures used were patient demographics, erectile function, residual curvature, patient satisfaction, graft area, and complications.ResultsAfter a mean follow-up of 17.8 months, no significant complication was noted. Complete penile straightening was achieved in all patients. The short side of the penis increased a mean of 3 cm in length, and the mean graft area was 12.4 cm2. At the end of the follow-up, three patients developed recurrent deformity. One patient presented severe fibrosis in the corpora cavernosa and severe ED. There was no significant difference between the mean preoperative and postoperative IIEF-5 scores (20.6 vs 19.4, respectively). At the end of follow-up, all patients were able to have sexual intercourse (two with and seven without pharmacological aid). Eight of the nine patients were satisfied with the surgical result.ConclusionPenile curvature surgical correction using the iGrafter seems to be an efficient and safe procedure, which uses minimum graft area and preserves erectile function after penile rectification, without resulting in residual deformities. Further research is needed to confirm the efficacy of this procedure.

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Section: Discussionmentioning

confidence: 98%

Practical Computerized Solution for Incision and Grafting in Peyronie's Disease

Miranda

Sampaio

2016

Sexual Medicine

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“…Autologous grafts were initially used for PD surgery in the 1950s [94] with different types of tissues, such as temporal fascia [95], buccal mucosa [96][97][98], deep dorsal vein [99], saphenous vein [100][101][102], preputium [103], dermis [71,[104][105][106], tunica albuginea [107][108][109], tunica vaginalis [110], fascia lata [111], and rectus sheath [112]. Some surgeons use saphenous vein due to its simplicity and reliability of harvesting, large surface area, good compliance, and lesser amount of intracavernosal fibrosis [1, 74•, 113].…”

Section: Tunical Lengthening Procedures (Grafting)mentioning

confidence: 99%

Treatment of Peyronie’s Disease: 2012 Update

Şerefoğlu

2011

Curr Urol Rep

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Peyronie's disease (PD) is the occurrence of a fibrous inelastic scar of the tunica albuginea of the penis. It is a relatively common disorder among men, with a reported prevalence of 3% to 8%. It is often associated with penile pain, anatomical deformities in the erect state, and difficulty with intromission. Because the exact pathophysiology of PD remains unknown and standards for evaluating or reporting treatment outcomes are unclear, research on effective therapies has been limited. The benefits of nonsurgical treatment options are conflicting and further controlled studies are required before any therapy can be fully recommended. The success of surgery has been well documented; however, surgery is invasive and costly and carries potential side effects. Patients who report stable disease that has been present for longer than 12 months and who experience penile deformity preventing satisfactory sexual intercourse are best suited for surgery. Additionally, failed conservative management and a patient's preference for definitive correction are important additional indications for surgical treatment.

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“…To my knowledge, the longevity/success of a particular grafting material is not related to the grafting technique provided that the graft has been properly installed. Since Lowsley and Boyce described the first penile graft for Peyronie's disease, the quest for the perfect graft commenced [15]. In 2002, Carson described the characteristics of the ideal graft [16].…”

Section: Introductionmentioning

confidence: 99%

Biomaterial Grafting Materials in Peyronie’s Disease

Bennett

2015

Curr Sex Health Rep

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Plaque incision/excision and grafting are a specialized procedure reserved for men with Peyronie's disease, featuring severe penile curvature, near-normal erectile function, and adequate erectile length. The choice of graft material requires careful consideration of the positive and negative attributes. Grafts may be divided into three distinct categories: synthetic, autologous, and extracellular materials. A description of each is presented below with a brief relevant literature review.

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Further Experiences with an Operation for Thecure of Peyronie’S Disease

Cited by 84 publications

References 5 publications

Practical Computerized Solution for Incision and Grafting in Peyronie's Disease

Practical Computerized Solution for Incision and Grafting in Peyronie's Disease

Treatment of Peyronie’s Disease: 2012 Update

Biomaterial Grafting Materials in Peyronie’s Disease

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