Further investigations on CR-39 fast neutron personal dosemeter

Djeffal, S.; Lounis, Zoubida; Allab, M.; Izerrouken, M.

doi:10.1016/s0168-9002(97)00786-9

Cited by 6 publications

(1 citation statement)

References 22 publications

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“…SSNTD have been used for multiple applications since their first description by Young (1958), including radon and uranium dosimetry (e.g., Stegnar et al, 2013; Hadad et al, 2013), personal neutron dosimetry (e.g., Djeffal et al, 1997; Saint Martin et al, 2011), and detection of cosmic rays (e.g., Dey et al, 2011). One of the outstanding applications includes mapping heavy particle emitters in mineral and biological materials (e.g., Armijo and Rosenbaum 1967; Bersina et al, 1995; Thellier et al, 2001, Rodrigues et al, 2013; Chauhan & Chauhan, 2014).…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Observation of Cells and Nuclear Tracks from the Boron Neutron Capture Reaction by UV-C Sensitization of Polycarbonate

Portu

Rossini²,

Thorp

et al. 2015

Microsc Microanal

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The distribution of boron in tissue samples coming from boron neutron capture therapy protocols can be determined through the analysis of its autoradiography image on a nuclear track detector. A more precise knowledge of boron atom location on the microscopic scale can be attained by the observation of nuclear tracks superimposed on the sample image on the detector. A method to produce an "imprint" of cells cultivated on a polycarbonate detector was developed, based on the photodegradation properties of UV-C radiation on this material. Optimal conditions to generate an appropriate monolayer of Mel-J cells incubated with boronophenylalanine were found. The best images of both cells and nuclear tracks were obtained for a neutron fluence of 1013 cm-2, 6 h UV-C (254 nm) exposure, and 4 min etching time with a KOH solution. The imprint morphology was analyzed by both light and scanning electron microscopy. Similar samples, exposed to UV-A (360 nm) revealed no cellular imprinting. Etch pits were present only inside the cell imprints, indicating a preferential boron uptake (about threefold the incubation concentration). Comparative studies of boron absorption in different cell lines and in vitro evaluation of the effect of diverse boron compounds are feasible with this methodology.

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