1962
DOI: 10.1016/0006-3002(62)91170-8
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Further observations on the biosynthesis of vitamin B12 inNocardia rugosa

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Cited by 13 publications
(4 citation statements)
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“…1). This route has already been suggested for Nocardia rugosa (2). However, the enzyme from P. denitrificans carries both cobalamin 5'-phosphate synthase and cobalamin synthase activities (Fig.…”
Section: Resultsmentioning
confidence: 55%
“…1). This route has already been suggested for Nocardia rugosa (2). However, the enzyme from P. denitrificans carries both cobalamin 5'-phosphate synthase and cobalamin synthase activities (Fig.…”
Section: Resultsmentioning
confidence: 55%
“…Methanogenic bacteria occur in habitats (28) which are enriched in corrinoids (5,12 (22), but this could not be demonstrated in Nocardia rugosa (4).…”
Section: Discussionmentioning
confidence: 96%
“…As shown first by DiMarco's group with N. rugosa (9, 77 ) and confi rmed by Bartosiriski with P. shermanii (16), the level if vitamin B12 rises upon administration of DBI to intact bacteria, while that of GDP-cobinamide falls. The Italian workers found, again, that N-a-glycosidic DBI-nttcleoside is incorporated into vitamin B12 with essentially no dilution from 14C_ labeled ribose added to the medium, while upon addition of free DBI and 14C-Iabeled ribose the nucleoside prepared from the isolated vitamin was radioactive (8). Hence, the bond between ribose and DBI is not split when N-a-glycosidically bound DBI is incorporated into vitamin Bu.…”
Section: From Cobinamide To the Completed Cob Amidementioning
confidence: 93%