In this paper, we extend Jacobson's lemma for Drazin inverses to the generalized \(n\)-strong Drazin inverses in a ring, and prove that \(1-ac\) is generalized \(n\)-strong Drazin invertible if and only if \(1-ba\) is generalized \(n\)-strong Drazin invertible, provided that \(a(ba)^{2}=abaca=acaba=(ac)^{2}a\). In addition, Jacobson's lemma for the left and right Fredholm operators, and furthermore, for consistent in invertibility spectral property and consistent in Fredholm and index spectral property are investigated.