In this study, the effects of powder filling were investigated on the natural amorphous silica at batch grinding conditions based on a kinetic model. For this purpose, firstly eight different mono-size fractions were carried out between 1.7 and 0.106 mm formed by a 2 sieve series.Then, Si and Bi,j equations were determined from the size distributions at different grinding times, and the model parameters (Si, aT, , , j and ) were compared for four different powder fillings (5, 10, 15 and 20%). Finally, model parameters for every test and interstitial filling fraction (U = fc/0.4 J) taking into consideration, the effects of the powder filling (fc) were discussed with respect to maximum mill capacity.In this study, it was found that the optimum value of U for the highest mill capacity is above 166.7% for an effective ratio for the natural amorphous silica. The effects of powder filling on the grinding process, this study found different results than other investigators.