Further understanding on osteopetrotic femoral fractures: a case report and literature review

Abstract

Background Osteopetrosis is a genetic disease characterized by defects in osteoclast formation and function. There were a few cases of subtrochanteric femur fractures treated with dynamic hip screw (DHS) in patients with osteopetrosis, but unfortunately the healing outcome was rather poor. Case presentation We present our experience for treating a patient with intermediate autosomal recessive osteopetrosis (IRO) suffering from subtrochanteric femur fracture. In this case, we successfully used dynamic hip screw (DHS) internal fixation through meticulous preoperative planning and postoperative care, as well as application of surgical techniques. The patient displayed stable internal fixation with no limitation of activities during follow-up for 15 months. In addition to this case, a review of previous case reports showed an increasing number of case reports demonstrating that surgical treatment-related complications could be avoided preoperatively, intraoperatively, and postoperatively. Conclusion DHS for this patient, who suffered from subtrochanteric fractures with osteopetrosis, was successfully implemented. In the light of a comprehensive literature review, preoperative planning, surgical techniques, and postoperative rehabilitation care can significantly reduce the complications.

Periprosthetic fracture of total hip replacement in patients with osteopetrosis: A case presentation and review of literature

“…However, as Ding et al highlight in their report, after 2005, with the accumulation of clinical and operative experience in the treatment of osteopetrosis-associated fractures, reports of complications after surgical treatment decreased significantly. They report that the complication rate decreased from 54.5% to 21% after 2005 12 .…”

Osteosynthesis of an intertrochanteric fracture on osteopetrosis A case report

“…Since Ding et al reported that occlusion of the medullary cavity and femoral malformation limited the application of intramedullary fixation, DHS fixation was used. At the same time, two sets of surgical instruments were prepared for use alternately, along with sterile ice-cold saline irrigation for cooling down, to solve the problem of overheating the drill, which aided the successful completion of the operation [ 9 ] ( Table 1 ).…”

“…At the same time, two sets of surgical instruments were prepared for use alternately, along with sterile ice-cold saline irrigation for cooling down, to solve the problem of overheating the drill, which aided the successful completion of the operation [ 9 ] ( Table 1 ).…”

Conversion Total Hip Arthroplasty in Patients With Osteopetrosis

“…T HA in patients with osteopetrosis has been reported as an effective procedure in treatment of osteoarthritis; however, it is a challenging procedure with prolonged operative time [3][4][5][6][7][8][9][10][11] . THA after prior surgical treatment of hip fracture is a technically demanding procedure 12 .…”