Global maritime accidents have a wide range of spatiotemporal differentiation characteristics, and it is an interesting problem that can be tried to seek efficient and scientific algorithms to recognize the spatiotemporal differentiation characteristics of global maritime accidents. Through the analysis of the data structure of marine traffic accidents, a global spatiotemporal differentiation analysis method for marine accidents based on accident point density clustering is proposed. A two-dimensional kernel density algorithm and a density-based clustering method with noise are introduced, and a clustering fusion algorithm based on spatial meshing and point density is established to reveal the spatiotemporal differentiation characteristics of global maritime accidents. Combined marine traffic accidents with the spatial and temporal information obtained on IMO GISIS in the past 30 years, the cluster fusion algorithm is applied to reveal spatiotemporal differentiation characteristics. The results show that the data efficiency of global maritime traffic accidents has been greatly improved with the wide application of AIS. The global maritime accident hot-spots are basically stable in Western Europe, the pan-Mediterranean and East Asia, South Asia, etc. Greater cooperation among neighboring port states, can effectively improve maritime traffic safety, especially in maritime search and recuse cooperation. The clustering fusion algorithm based on spatial meshing and point density can be further applied to the scenarios application in the regional scope, so as to clearly reflect the temporal and spatial differentiation characteristics of maritime accidents in the scenarios.