The Lawson criterion constitutes a pivotal condition for the viability of sustained fusion reactions. This study employs numerical methods and data analysis in Microsoft Excel to ascertain the Lawson criterion for D-³He fusion at temperatures ranging from 75 to 150 keV. Furthermore, the investigation examines the influence of bremsstrahlung radiation and evaluates fusion reactivity based on Hively and Bosch-Hale parameters. Hively’s reactivity value falls within the range of 1.121 × 10−22 – 6.750 × 10−22 m3/s, the instability occurs at temperatures < 100 keV. The Bosch-Hale value differs significantly from the Hively reactivity, which is 1.208 × 10−22 – 2.340 × 10−22 m3/s. The bremsstrahlung radiation within the range of 4.819 × 10−20 – 6.802 × 10−20 keV exhibits minimal impact on the reaction. The Lawson criterion value within the scope of this study typically falls within the range of 0.437 × 1021 – 1.452 × 1021 s/m3. This range signifies the necessary combination of confinement time and plasma density to facilitate the generation of clean energy within a temperature range of 75 to 150 keV, thus propelling the fusion process toward the ignition phase.