“…1,[18][19][20]23,29,31 Given the favorable proximity of the spinous processes, one can achieve robust sagittal stability while largely preserving the paraspinal muscles, avoiding the posterior neural elements, and conserving the facets. 1,[18][19][20]23,29,31,40 However, despite such biomechanical and perioperative benefits, reports of midterm and long-term clinical outcomes with ISPF are limited and retrospective in design. 41 Accordingly, the purpose of this prospective, randomized, controlled, multicenter clinical trial was to assess intraoperative outcomes, patientreported outcomes, radiographic success, concomitant medication usage, neurologic status, and complication profiles in patients receiving singlelevel ALIF/LLIF with supplemental ISPF for degenerative pathology.…”