Future integration of silicon electronics with miniature piezoelectric ultrasonic transducers and arrays

Cochran, Sandy; Bernassau, A.L.; Cumming, David R. S.; Démoré, Christine; Desmulliez, Marc Phillipe Yves; Sweet, J.

doi:10.1109/ultsym.2010.5935950

Cited by 6 publications

(3 citation statements)

References 42 publications

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“…1). The current generation of scanners include 1½ and 2-dimensional arrays allowing improved in-and out-of-plane (elevational) focusing, rapid image processing, and 3-D and 4-D imaging (real-time volumetric imaging) (47)(48)(49)(50)(51)(52) (Fig. 7, Fig.…”

Section: Fig 1 a Compact Ultrasound System With Wireless Chargeable T...mentioning

confidence: 99%

Musculoskeletal ultrasound: a technical and historical perspective

Adler

2023

J Ultrason

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During the past four decades, musculoskeletal ultrasound has become popular as an imaging modality due to its low cost, accessibility, and lack of ionizing radiation. The development of ultrasound technology was possible in large part due to concomitant advances in both solid-state electronics and signal processing. The invention of the transistor and digital computer in the late 1940s was integral in its development. Moore’s prediction that the number of microprocessors on a chip would grow exponentially, resulting in progressive miniaturization in chip design and therefore increased computational power, added to these capabilities. The development of musculoskeletal ultrasound has paralleled technical advances in diagnostic ultrasound. The appearance of a large variety of transducer capabilities and rapid image processing along with the abil- ity to assess vascularity and tissue properties has expanded and continues to expand the role of musculo- skeletal ultrasound. It should also be noted that these developments have in large part been due to a number of individuals who had the insight to see the potential applications of this developing technology to a host of relevant clinical musculoskeletal problems. Exquisite high-resolution images of both deep and small super- ficial musculoskeletal anatomy, assessment of vascularity on a capillary level and tissue mechanical proper- ties can be obtained. Ultrasound has also been recognized as the method of choice to perform a large variety of interventional procedures. A brief review of these technical developments, the timeline over which these improvements occurred, and the impact on musculoskeletal ultrasound is presented below.

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Section: Fig 1 a Compact Ultrasound System With Wireless Chargeable T...mentioning

confidence: 99%

Musculoskeletal ultrasound: a technical and historical perspective

Adler

2023

J Ultrason

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“…It is also possible to integrate piezoelectric materials in thick [53] or thin film [54,55] form, or indeed bonded bulk material [56], with other components. Requiring an additional level of fabrication sophistication, typically including photolithography [57], this approach may be very useful when the number of devices is high and may be a key issue in differentiating acoustic manipulation from optical manipulation [58], where integration is still much harder.…”

Section: Limitations and Typical Parameters For On-chip Manipulationmentioning

confidence: 99%

Ultrasound assisted particle and cell manipulation on-chip

Mulvana

Cochran

Hill

2013

Advanced Drug Delivery Reviews

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Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including microbubbles. The technology is compatible with existing lab-on-chip techniques and is complementary to many alternative manipulation approaches due to its ability to handle many cells simultaneously over extended length scales. This paper provides an overview of the physical principles underlying ultrasonic manipulation, discusses the biological effects relevant to its use with cells, and describes emerging applications that are of interest in the field of drug development and delivery on-chip.

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“…An inverse filtering approach more fully measures all mechanisms of image degradation, including aberration by the near skull, path-dependent aberration, and path-dependent attenuation, although when applied to skull aberrations, it uses a phase screen assumption in approximating the propagation operator as a diagonal matrix [40]. However, the cost of implementing this approach on a 2-D array is significant, requiring a fully programmable transmitter and access to the RF signal for each element, a difficult proposition at a time when many manufacturers have moved toward digitization and partial beamforming in the probe handle [76], [77]. In this work, it is assumed that aberration effects from the first skull transit are small relative to aberration effects resulting from the second skull transit, because wave divergence and path-dependent effects tend to average out any initial aberrations, whereas aberration effects caused by the second skull transit are directly measured immediately after they occur.…”

Section: Introductionmentioning

confidence: 99%

Pitch-catch phase aberration correction of multiple isoplanatic patches for 3-D transcranial ultrasound imaging

Lindsey

Smith

2013

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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Having previously presented the ultrasound brain helmet, a system for simultaneous 3-D ultrasound imaging via both temporal bone acoustic windows, the scanning geometry of this system is utilized to allow each matrix array to serve as a correction source for the opposing array. Aberration is estimated using cross-correlation of RF channel signals, followed by least mean squares solution of the resulting overdetermined system. Delay maps are updated and real-time 3-D scanning resumes. A first attempt is made at using multiple arrival time maps to correct multiple unique aberrators within a single transcranial imaging volume, i.e., several isoplanatic patches. This adaptive imaging technique, which uses steered unfocused waves transmitted by the opposing, or beacon, array, updates the transmit and receive delays of 5 isoplanatic patches within a 64° × 64° volume. In phantom experiments, color flow voxels above a common threshold have also increased by an average of 92%, whereas color flow variance decreased by an average of 10%. This approach has been applied to both temporal acoustic windows of two human subjects, yielding increases in echo brightness in 5 isoplanatic patches with a mean value of 24.3 ± 9.1%, suggesting that such a technique may be beneficial in the future for performing noninvasive 3-D color flow imaging of cerebrovascular disease, including stroke.

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Future integration of silicon electronics with miniature piezoelectric ultrasonic transducers and arrays

Cited by 6 publications

References 42 publications

Musculoskeletal ultrasound: a technical and historical perspective

Musculoskeletal ultrasound: a technical and historical perspective

Ultrasound assisted particle and cell manipulation on-chip

Pitch-catch phase aberration correction of multiple isoplanatic patches for 3-D transcranial ultrasound imaging

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