China is in a development period of urbanization construction, while its environment is threatened by an increasing amount of construction and demolition (C&D) waste. Due to the excessive pursuit of profits and a general lack of environmental awareness of stakeholders, illegal behaviors such as illegal dumping universally exist in the waste disposal process. Meanwhile, supervision departments face many challenges in collaborative management and decision-making, which lead to inefficiencies in C&D waste supervision and management in China. To address the above challenges, we propose an informatization scheme integrating multiple technologies, which will contribute to real-time monitoring of illegal behaviors in the waste disposal process, accurate data collection for evaluating the performance of stakeholders, and the enhancement of the collaboration between supervisory departments. A case study of the Ningbo Construction Waste Transportation Supervision System is introduced to verify the feasibility and effectiveness of the proposed scheme; results show that the total number of illegal cases has decreased from 510 to 89 per year since the system was put into operation.