Future Research on the Role of the Mesentery in Health and Disease

Ehrenpreis, Eli D.; Wexner, Steven D.; Alverdy, John C.; Kruchko, David H.

doi:10.1007/978-3-030-71963-0_50

Cited by 2 publications

(3 citation statements)

References 11 publications

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“…Volvulus can occur anywhere on the length of the colon although it is more common in the sigmoid colon. In patients with a significant redundant bowel, post operatively, there may be further episodes of volvulus this may be due to inadequate sigmoid resection however also can be due to volvulus in the caecum or even in the transverse colon 14 .…”

Section: I) Discussionmentioning

confidence: 99%

Outcome of Sigmoid Colectomy in patients with recurrent Sigmoid Volvulus. A single center experience from a Rural Hospital

Gandiya¹

2022

Isra Med J

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Objective: To assess the outcomes of definitive surgical management (sigmoid colectomy) in recurrent sigmoid volvulus. Study Design: Retrospective analytic study. Place and Duration: Department of Surgery at Balfour Hospital, Orkney, Scotland from 1st September 2014 to 1st September 2021. Methodology: Data of patients admitted with recurrent volvulus for three or more times and selected for surgery by a multiple disciplinary team retrieved. The median follow up of 32 (5-60) months was analyzed. The demographic features of the patient, symptoms, and complications after surgery, number of admissions before and after surgery and patient quality of life before and after surgery were analyzed. Results: A total of 33 patients were analyzed with an age ranges from 35 to 76 years with a median age of 55.5 years, M:F ratio of 12:2 and with duration of symptomatic volvulus 12 to 36 (median 24) months. Of the patients in the study, 24 patients had three previous admissions and 9 had more than three admissions with sigmoid volvulus that was managed conservatively. Complications experienced included post-operative ileus in 33.3%, wound infection 6%, and readmission with volvulus was 3.03% however 57.5% reported no complications. Conclusion: Our study concluded an excellent intermediate term outcome with very low clinical recurrence in patients who were offered definitive management following multiple admissions. Keywords: Sigmoid volvulus, Recurrent, Co-morbidities, Colectomy, Complications, Outcome

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Section: I) Discussionmentioning

confidence: 99%

Outcome of Sigmoid Colectomy in patients with recurrent Sigmoid Volvulus. A single center experience from a Rural Hospital

Gandiya¹

2022

Isra Med J

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“…Clarification of the anatomical properties of the mesentery enabled systematic characterization of it in diseases such as Crohn's disease. 9 The findings that emerge demonstrate a strong coupling of mesenteric abnormality and intestinal inflammation (►Fig. 3).…”

Section: Do Mesenteric Events Exert a Net Pathogenic Or Beneficial Ef...mentioning

confidence: 99%

“…[4][5][6] This coincided with clarification of the anatomical properties of the mesentery. [7][8][9] Until this clarification the mesentery was described as absent at some levels of the intestine, and present at others. [10][11][12][13] Given that Crohn's disease can affect all levels of the intestine, it is unlikely that the mesentery of conventional descriptions could be involved in its etiology and pathogenesis.…”

Section: The Mesentery Clarifiedmentioning

confidence: 99%

The Surgical Management of the Mesentery in Crohn's Disease

Coffey,

Devine

2024

Clin Colon Rectal Surg

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Increasing evidence suggests that Crohn's disease is a primary mesenteropathy and that resection of the mesentery, or its exclusion from an anastomosis, may alter disease progression. If borne out in clinical trials, this observation would be welcome, as current pharmacotherapeutic approaches to Crohn's disease appear to have limited effect on disease progression. This article explores arguments for and against the alteration of mesenteric inputs by surgical means, in Crohn's disease.

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Future Research on the Role of the Mesentery in Health and Disease

Cited by 2 publications

References 11 publications

Outcome of Sigmoid Colectomy in patients with recurrent Sigmoid Volvulus. A single center experience from a Rural Hospital

Outcome of Sigmoid Colectomy in patients with recurrent Sigmoid Volvulus. A single center experience from a Rural Hospital

The Surgical Management of the Mesentery in Crohn's Disease

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