Future risk of diabetes among Indians with metabolic and phenotypic obesity: Results from the 10-year follow-up of the Chennai Urban Rural Epidemiology Study (CURES–158)

Natarajan, Hariharasudan; Rani, Coimbatore Subramanian Shanthi; Kumar, Dharman Krishna; Anjana, Ranjit Mohan; Unnikrishnan, Ranjit; Venkatesan, Ulagamathesan; Sankari, Ganesan Uma; Pradeepa, Rajendra; Mohan, Viswanathan; Deepa, Mohan

doi:10.1007/s00592-021-01698-7

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Cited by 4 publications

References 24 publications

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Associations between metabolic phenotypes and diabetes risk: A systematic review and meta-analysis

Vera-Ponce,

Loayza-Castro,

Zuzunaga-Montoya

et al. 2023

Endocrine and Metabolic Science

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Associations between metabolic phenotypes and diabetes risk: A systematic review and meta-analysis

Vera-Ponce,

Loayza-Castro,

Zuzunaga-Montoya

et al. 2023

Endocrine and Metabolic Science

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Serum oxidized low density lipoprotein serves as a mediator for the inverse relationship between serum d-ribose and cognitive performance in type 2 diabetic patients

Jiang

Zhang

et al. 2021

Free Radical Biology and Medicine

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Understanding the predictive accuracy of the InsuTAG index over other surrogate indices in normoglycaemic, non-obese males from Southern India

Jebasingh,

Anoop,

Dasgupta

et al. 2023

Sci Rep

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We aimed to evaluate the predictive accuracy of InsuTAG index against M value of the hyperinsulinaemic-Euglycaemic clamp (HEC) procedure and fasting surrogate indices of insulin sensitivity/resistance in young, normoglycaemic, Asian Indian males. HEC studies were done in young (mean age 19.7 ± 1 years), non-obese (mean BMI 19.2 ± 2.6 kg/m2), normoglycemic Asian Indian males (n = 110) and the M value was calculated. Surrogate indices namely InsuTAG index, HOMA-IR, FG-IR, QUICKI and McAuley index were calculated. Pearson’s correlation and ROC-AUC at 95% CI were applied. Significant negative correlation was observed for InsuTAG index with the M value (r − 0.23, p = 0.01), McAuley index (r − 0.65, p < 0.01), QUICKI (r − 0.34, p < 0.01) and FGIR (r − 0.35, p < 0.01). Significant positive correlations of InsuTAG index were observed for BMI and waist circumference. The ROC-AUC was higher for InsuTAG index (0.75) than FGIR (0.30), QUICKI (0.31), and McAuley index (0.20). The InsuTAG cut-off value ≥ 19.13 showed 66.7% sensitivity and 69.2% specificity in this study group.

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Future risk of diabetes among Indians with metabolic and phenotypic obesity: Results from the 10-year follow-up of the Chennai Urban Rural Epidemiology Study (CURES–158)

Cited by 4 publications

References 24 publications

Associations between metabolic phenotypes and diabetes risk: A systematic review and meta-analysis

Associations between metabolic phenotypes and diabetes risk: A systematic review and meta-analysis

Serum oxidized low density lipoprotein serves as a mediator for the inverse relationship between serum d-ribose and cognitive performance in type 2 diabetic patients

Understanding the predictive accuracy of the InsuTAG index over other surrogate indices in normoglycaemic, non-obese males from Southern India

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