This paper proposes a fault-tolerant cooperative control (FTCC) scheme for multiple UAVs in a distributed communication network against input saturation, full-state constraints, actuator faults, and unknown dynamics. Firstly, by considering physical limitations, an auxiliary control signal is designed to simplify the analysis process. Secondly, to avoid the difficulty in the back-stepping design caused by full-state constraints, virtual control signals are constructed to transform constrained variables, while the dynamic surface control is adopted to avoid the phenomenon of “differential explosion.” Thirdly, a disturbance observer (DO) is designed to estimate the unknown uncertainty caused by parameter uncertainty and actuator fault. Moreover, a recurrent wavelet fuzzy neural network (RWFNN) is used to compensate for the estimation errors of DO. Finally, it is proved that all states are uniformly ultimately bounded (UUB) by Lyapunov and invariant set theory. The effectiveness of the proposed scheme is further demonstrated by the simulation results.