Self-tuning fuzzy logic controllers (STFLC) for the active control of Marmara Kocaeli earthquake excited building structures are studied in this paper. Vibration control using intelligent controllers, such as fuzzy logic has attracted the attention of structural control engineers during the last few years, because fuzzy logic can handle nonlinearities, uncertainties, and heuristic knowledge effectively and easily. The improved seismic control performance can be achieved by converting a simply designed static gain into a real time variable dynamic gain through a selftuning mechanism. Self-tuning fuzzy logic controller is designed to reduce the story-drift of each floor.The simulated system has a nine-degree-of-freedom, which is modeled using nonlinear behavior of the base-structure interaction. Modeled system was simulated against the ground motion of the Marmara Kocaeli earthquake (M w = 7.4) in Turkey on 17 August, 1999. At the end of the study, the time history of the story displacements, accelerations, ATMD displacements, control voltage, and frequency responses of the both uncontrolled and controlled cases are presented. The robustness of the controller has been checked through the uncertainty in stiffness of the structure. Performance of the designed STFLC has been demonstrated for the different disturbance using ground motion of the Kobe earthquake. Simulations of an earthquake excited nine story structure are performed to prove the validity of proposed control strategy.