FWHM and Sensitivity Study of Bimetallic SPR Sensor Chip

Recent Advances in Surface Plasmon Resonance for Biosensing Applications and Future Prospects

“…In their results, the obtained value of Full Width at Half Maximum (FWHM) with the bimetallic film was found to be much smaller than that of the pure gold film, while the stability of the bimetallic film was found to be better than that of the pure silver film [87]. In our recent study, we also emphasized on parameters such as full width at half maxima (FWHM) and sensitivity of a set of three bimetallic sensors are prepared by varying the metal film type and thickness [88]. The samples and their specifications are indicated the Table II.…”

Multiple protein‐patterned surface plasmon resonance biochip for the detection of human immunoglobulin‐G

“…Finally, the substrates were rinsed with DI water and dried. A layer of titanium (Ti) ($5 nm) was then deposited on one side of the cleaned substrates using RF magnetron sputtering technique at a deposition rate of 0.2 Angstroms per sec followed by the deposition of gold (Au) ($50 nm) using DC magnetron sputtering at a deposition rate of 0.5 Angstroms per sec to promote surface adhesion of gold film to glass [54,55]. The RF and DC magnetron sputtered thin films were deposited using argon (Ar) gas at the deposition pressure of 6 Â 10 À6 mbar at room temperature of 25 C. Figure 3 shows the schematic diagram of the protocol used for bonding gold substrate with PDMS microfluidic chip for the immobilization of the polyclonal antibodies.…”

“…Over the years, several microfluidic integrated portable Kretschmann angular configured SPR measurement devices have been designed and fabricated for detection of protein, DNA, and so on [54][55][56][57][58]. They present several merits such as establishing an array of SPR spots, precise, and low volume sample delivery which helps in achieving high sensitivities and low limit of detection.…”