2006
DOI: 10.1111/j.1365-2141.2006.06463.x
|View full text |Cite
|
Sign up to set email alerts
|

G6PD Namoru (208 T→ C) is the major polymorphic variant in the tribal populations in southern India

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
11
0

Year Published

2007
2007
2024
2024

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 12 publications
(11 citation statements)
references
References 3 publications
0
11
0
Order By: Relevance
“…45 For example, G6PD Namoru is the major polymorphic variant in the tribal populations in southern India. 50 In Latin America, the prevalence of G6PD deficiency is generally low (< 2%, Table 1), and G6PD A− appears to be the most common deficient variant. [32][33][34] In Brazil, 98.6% of G6PD-deficient blood bank samples were G6PD A−, with only 1 of 4,621 samples G6PD Mediterranean.…”
Section: Molecular Epidemiology Of G6pd Deficiencymentioning
confidence: 99%
“…45 For example, G6PD Namoru is the major polymorphic variant in the tribal populations in southern India. 50 In Latin America, the prevalence of G6PD deficiency is generally low (< 2%, Table 1), and G6PD A− appears to be the most common deficient variant. [32][33][34] In Brazil, 98.6% of G6PD-deficient blood bank samples were G6PD A−, with only 1 of 4,621 samples G6PD Mediterranean.…”
Section: Molecular Epidemiology Of G6pd Deficiencymentioning
confidence: 99%
“…G6PD Mediterranean was found to have significantly lower red cell enzyme activity and more severe clinical manifestations than the other two 22 . Of the three common mutations, G6PD Odisha and G6PD Mediterranean were found to be the main mutational event causing G6PD deficiency among the tribal groups of Maharashtra, Odisha and Gujarat 23 24 25 26 while G6PD Namoru (208 T→C) was exclusively found among the Dravidian speaking tribes of Nilgiri district, Tamil Nadu, which further supported the human migration from Africa to Australia along the coast of southern India 27 . Besides these mutations, G6PD Chatam, G6PD Coimbra, G6PD Nilgiri, and G6PD Gond have also been reported in the Indian tribal populations 25 28 29 .…”
Section: Molecular Pathology Of G6pd Deficiencymentioning
confidence: 72%
“…While it also constitutes a relevant factor in India, explaining around 24% of G6PD deficiencies in a country-wide survey, the overall most prevalent allele was Orissa, which accounted for 57% of all deficiencies (Devendra et al 2020 ). Further rare variants of relevance in specific South Asian subpopulations and tribal groups are Kalyan–Kerala and Namoru (Chalvam et al 2007 ). In Southeast Asia, the predominant allele is Mahidol, which explains 38–96% in of G6PD deficiencies in Burma, Thailand and Myanmar (Matsuoka et al 2004 ; Phompradit et al 2011 ).…”
Section: G6pdmentioning
confidence: 99%