Abstract:Conclusion Regular nitrous oxide abuse causes an active vitamin B12 deficiency; usually total vitamin B12 is normal and more sensitive markers including homocysteine, methylmalonic acid (MMA) and active vitamin B12 are needed for diagnosis. Nitrous oxide abuse is commonplace amongst teenagers and young adults, it is important that paediatricians are made aware of how commonly it is abused and the neurological consequences. Nitrous oxide is cheap and easy to obtain; particularly as it can be bought legally for … Show more
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