In Chapter 3, the theoretical considerations relevant to various types of waveguides were discussed. In every case, waveguiding depended on the difference in the index of refraction between the waveguiding region and the surrounding media. A great many techniques have been devised for producing that required index difference. Each method has particular advantages and disadvantages, and no single method can be said to be clearly superior. The choice of a specific technique of waveguide fabrication depends on the desired application, and on the facilities available. In this Chapter, various methods of waveguide fabrication are reviewed, and their inherent features are discussed.