2024
DOI: 10.3390/biomedicines12122905
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GABALAGEN Alleviates Stress-Induced Sleep Disorders in Rats

Hyun-Jung Park,
Sung Ja Rhie,
Woojin Jeong
et al.

Abstract: (1) Background: Gamma-aminobutyric acid (GABA) is an amino acid and the primary inhibitory neurotransmitter in the brain. GABA has been shown to reduce stress and promote sleep. GABALAGEN (GBL) is the product of fermented fish collagen by Lactobacillus brevis BJ20 and Lactobacillus plantarum BJ21, naturally enriched with GABA through the fermentation process and characterized by low molecular weight. (2) Methods: The present study evaluated the GABAAing affinity of GBL through receptor binding assay. The sedat… Show more

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