Gabapentin and Pregabalin in the Management of Postoperative Pain After Lumbar Spinal Surgery

Lin, Yi-Hsiu; Ran, Bo; Li, Min; Shi, Zhi-Cai

doi:10.1097/brs.0b013e3182a69b90

Cited by 105 publications

(81 citation statements)

References 18 publications

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“…Additionally, both gabapentinoids reduced the amount of opioid consumption versus placebo [33]. In a systematic review and meta-analysis of randomized controlled trials, Yu et al found that both gabapentin and pregabalin were efficacious in reducing postoperative pain and narcotic requirements after lumbar spinal surgery [34].…”

Section: Anticonvulsants/calcium Channel A2-d Ligandsmentioning

confidence: 99%

Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes

Devin

McGirt

2015

Journal of Clinical Neuroscience

203

133

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Section: Anticonvulsants/calcium Channel A2-d Ligandsmentioning

confidence: 99%

Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes

Devin

McGirt

2015

Journal of Clinical Neuroscience

203

133

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“…Indeed, procedure-specific meta-analyses still suffer from considerable statistical heterogeneity. 108 Therefore, we could find little empirical basis for conducting such procedure-specific reviews for adjuvant analgesics. However, we accept that this finding contradicts both previous research and clinical intuition.…”

Section: Discussionmentioning

confidence: 99%

Baseline Morphine Consumption May Explain Between-Study Heterogeneity in Meta-analyses of Adjuvant Analgesics and Improve Precision and Accuracy of Effect Estimates

Doleman

Sutton

Sherwin

et al. 2018

Anesthesia &Amp; Analgesia

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“…In fact, preoperative administration of acetaminophen and gabapentin have been shown to decrease opioid requirements, improve functional outcome, and increase patient satisfaction postoperatively [16][17][18]. These drugs may also decrease preoperative anxiety, pruritus, and postoperative shivering [19].…”

Section: Non-opioid Analgesicsmentioning

confidence: 99%

The Elderly Spine Surgery Patient: Pre- and Intraoperative Management of Drug Therapy

Brallier

Deiner

2015

Drugs Aging

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Spine surgery is one of the most common surgeries for adults greater than 65 years of age. Optimizing and caring for the elderly patient presenting for spine surgery requires planning and multidisciplinary input from surgeons, primary care physicians, and anesthesiologists. Controversies exist surrounding appropriate perioperative management of complicated chronic medication regimens and the ideal selection of intraoperative therapy for these patients. In this article we present an overview of the controversies anesthesiologists face as they work with the elderly patient's primary doctor and surgical team to achieve a safe perioperative course. Specifically, we discuss the interaction of geriatric physiology and pathophysiology with medications used in the perioperative period. While care of the geriatric spine surgery patient is nuanced, the anesthesiologist can work together with medical personnel, surgeons, and pharmacy to provide safe and effective care. Key PointsSpine surgery is one of the five most common surgeries for older adults.Optimizing and caring for the elderly patient presenting for spine surgery requires planning and multidisciplinary input from surgeons, primary care physicians, and anesthesiologists.Controversies exist surrounding appropriate perioperative management of complicated medication regimens and the ideal manner in which to care for these patients.Continuation of chronic medications, selection of intraoperative medications, and plan for postoperative pain control are strongly influenced by the surgical plan.

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Gabapentin and Pregabalin in the Management of Postoperative Pain After Lumbar Spinal Surgery

Abstract: 1.

Cited by 105 publications

References 18 publications

Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes

Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes

Baseline Morphine Consumption May Explain Between-Study Heterogeneity in Meta-analyses of Adjuvant Analgesics and Improve Precision and Accuracy of Effect Estimates

The Elderly Spine Surgery Patient: Pre- and Intraoperative Management of Drug Therapy

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