In the present study, physico-chemically pre-treated textile wastewater with a residual chemical oxygen demand (COD) of 780 ± 10 mg L −1 was treated using a lab-scale upflow anaerobic sludge blanket (UASB) reactor at variable HRTs of 30.8 to 8 h, and organic loading rates (OLRs) of 0.62-2.4 kg COD m −3 d −1 . Using a new composite coagulant at dosage of 800 mg L −1 for pre-treatment, more than 99% of colour was removed from the feeding influent to UASB reactor. The optimum OLR was found as 0.95 kg COD m −3 d −1 at which maximum COD reduction (98%) was achieved. Modified Stover-Kincannon, Grau second-order, Monod, Haldane and Contois models were applied to evaluate the carbonaceous substrate removal kinetics inside the UASB reactor. The experimental results of this analysis revealed that modified Stover-Kincannon and Grau second-order kinetics were suitable for predicting the performance and to estimate the kinetic coefficients of UASB reactor.