Gadolinium-loaded LTL nanosized zeolite for efficient oxygen delivery and magnetic resonance imaging

Amedlous, Abdallah; Hélaine, Charly; Guillet‐Nicolas, Rémy; Lebedev, Oleg I.; Valable, Samuel; Mintova, Svetlana

doi:10.1039/d3qi00169e

Cited by 2 publications

(2 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…53 Lanthanides, such as paramagnetic Gd, have been incorporated in zeolites for biomedical applications such as magnetic resonance imaging. 54 Zeolite Frameworks. Zeolite frameworks can be divided into different categories based on their maximum ring size.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

See 1 more Smart Citation

ZeoSyn: A Comprehensive Zeolite Synthesis Dataset Enabling Machine-Learning Rationalization of Hydrothermal Parameters

Pan,

Kwon,

Jensen

et al. 2024

ACS Cent. Sci.

View full text Add to dashboard Cite

Zeolites, nanoporous aluminosilicates with well-defined porous structures, are versatile materials with applications in catalysis, gas separation, and ion exchange. Hydrothermal synthesis is widely used for zeolite production, offering control over composition, crystallinity, and pore size. However, the intricate interplay of synthesis parameters necessitates a comprehensive understanding of synthesis–structure relationships to optimize the synthesis process. Hitherto, public zeolite synthesis databases only contain a subset of parameters and are small in scale, comprising up to a few thousand synthesis routes. We present ZeoSyn, a dataset of 23,961 zeolite hydrothermal synthesis routes, encompassing 233 zeolite topologies and 921 organic structure-directing agents (OSDAs). Each synthesis route comprises comprehensive synthesis parameters: 1) gel composition, 2) reaction conditions, 3) OSDAs, and 4) zeolite products. Using ZeoSyn, we develop a machine learning classifier to predict the resultant zeolite given a synthesis route with >70% accuracy. We employ SHapley Additive exPlanations (SHAP) to uncover key synthesis parameters for >200 zeolite frameworks. We introduce an aggregation approach to extend SHAP to all building units. We demonstrate applications of this approach to phase-selective and intergrowth synthesis. This comprehensive analysis illuminates the synthesis parameters pivotal in driving zeolite crystallization, offering the potential to guide the synthesis of desired zeolites. The dataset is available at .

show abstract

Section: ■ Results and Discussionmentioning

confidence: 99%

“…Zeolites have served as supports for transition metal catalysts, like Co and Ni, to obtain fuels from syngas and CO 2 methanation . Lanthanides, such as paramagnetic Gd, have been incorporated in zeolites for biomedical applications such as magnetic resonance imaging …”

Section: Results and Discussionmentioning

confidence: 99%

ZeoSyn: A Comprehensive Zeolite Synthesis Dataset Enabling Machine-Learning Rationalization of Hydrothermal Parameters

Pan,

Kwon,

Jensen

et al. 2024

ACS Cent. Sci.

View full text Add to dashboard Cite

show abstract

Gas Delivery Relevant to Human Health using Porous Materials

Mandel,

Lotlikar,

Keasler

et al. 2024

Chemistry A European J

View full text Add to dashboard Cite

Gases are essential for various applications relevant to human health, including in medicine, biomedical imaging, and pharmaceutical synthesis. However, gases are significantly more challenging to safely handle than liquids and solids. Herein, we review the use of porous materials, such as metal‐organic frameworks (MOFs), zeolites, and silicas, to adsorb medicinally relevant gases and facilitate their handling as solids. Specific topics include the use of MOFs and zeolites to deliver H2S for therapeutic applications, 129Xe for magnetic resonance imaging, O2 for the treatment of cancer and hypoxia, and various gases for use in organic synthesis. This Perspective aims to bring together the organic, inorganic, medicinal, and materials chemistry communities to inspire the design of next‐generation porous materials for the storage and delivery of medicinally relevant gases.

show abstract

Gadolinium-loaded LTL nanosized zeolite for efficient oxygen delivery and magnetic resonance imaging

Abstract: The search for efficient gas carriers for biomedical applications presents a challenging task due to the kinetics of gas adsorption/desorption. This article presents a novel approach utilizing Gd-LTL zeolite crystals for oxygen delivery combined with an MRI study.

Cited by 2 publications

References 48 publications

ZeoSyn: A Comprehensive Zeolite Synthesis Dataset Enabling Machine-Learning Rationalization of Hydrothermal Parameters

ZeoSyn: A Comprehensive Zeolite Synthesis Dataset Enabling Machine-Learning Rationalization of Hydrothermal Parameters

Gas Delivery Relevant to Human Health using Porous Materials

Contact Info

Product

Resources

About