Gadoxetate Disodium-Enhanced Magnetic Resonance Imaging Versus Contrast-Enhanced 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for the Detection of Colorectal Liver Metastases

Abstract

: EOB-MRI using a 3-T system is more accurate than CE-PET/CT, especially for the detection of small (≤1.0 cm) lesions. Patient-based analysis revealed that EOB-MRI has a higher sensitivity and negative predictive value than CE-PET/CT.

Safety of Gadopentetate Dimeglumine after 120 Million Administrations over 25 Years of Clinical Use

“…Advances in hardware and software that have enhanced the signal-tonoise ratio and improvements in contrast resolution with gadolinium-based contrast agents (GBCAs) 1 make contrast-enhanced MR imaging (CE-MRI) a comparable or better diagnostic tool than computed tomography and other conventional imaging methods. [2][3][4][5] Further advances in dynamic CE-MRI perfusion 6 and contrast-enhanced magnetic resonance angiography (MRA) 7 have improved the e‹ciency of clinical diagnoses, and highlight the importance of imaging techniques in diagnostic medicine.…”

Meta‐analysis of diagnosis of liver metastatic cancers: Comparison of 18FDG PET‐CT and gadolinium‐enhanced MRI

“…However, the differences in the efficacy between 18 FDG PET-CT and gadolinium-enhanced MRI have not been clearly delineated. In the five included studies, 1,7,9,18,19 gadolinium-enhanced MRI tends to have higher sensitivity than FDG PET-CT tends to have higher sensitivity than gadolinium-enhanced MRI in the three included studies (1.00 vs 0.93, 1.00 vs 0.96 and 1.00 vs 0). 10,11,13 There are still two studies in which 18 FDG PET-CT have the same sensitivity with gadolinium-enhanced MRI (0.89 vs 0.89 and 1.00 vs 1.00).…”

“…In two 15,20 of 10 articles, the study design was retrospective. In two studies (357 patients), 7,8 only patients with lung cancer were enrolled, in another two studies (102 patients), 10,19 only patients with colorectal cancer were enrolled, in four studies (511 patients), 9,12,13,18 only patients with head and neck cancer were enrolled, and in two studies (135 patients), 1,11 mixed patient populations were enrolled.…”

Rendimiento del Positron Emission Tomography/Computed Tomography (PET/CT) en etapificación de cáncer pulmonar

“…Esta caracterís-tica es de suma importancia al querer diferenciar lesiones benignas hepáticas, de alta incidencia en la población adulta, de lesiones malignas secundarias y explica la alta especificidad del PET en lesiones focales del hígado 4 . Por otro lado, la técnica híbri-da PET/CT potencia la sensibilidad de la TCc, que fluctúa entre 73 y 85%, llevándola hasta 93-97% en la detección de metástasis hepáticas 15,16 . Si bien las lesiones secundarias cerebrales no son las más frecuentes en esta población, su importancia radica en que su presencia determina una alta morbi-mortalidad, que en algunos casos puede ser evitada o al menos disminuida con un adecuado tratamiento.…”