The vapor phase chelate delivery (VPCD) technique in conjunction with the modified chemical vapor deposition (MCVD) process is adopted to fabricate fibers with customized doping profiles. The three large‐mode area (LMA) step‐index fibers with different rare‐earth doping profiles in the core region, such as uniform doping, centralized doping, and circumferential doping, are fabricated by optimizing the fabrication parameters. The fibers are tested in a cladding‐pumped amplifier configuration and their output beam qualities and signal‐to‐noise ratio (SNR) are characterized. The investigation reveals that the fiber with centralized doping in the core region exhibits lower M
2 compared with the fibers with uniform and circumferential doping, as it has a lower overlap of the higher‐order modes with the doped region. The experimental result is further affirmed through theoretically simulated results. The developed fabrication technique shows potential to fabricate specialty fibers of varied designs, where customized doping profiles are required.