Gaitada Gizli Kan Pozitifliği Nedeniyle Kolonoskopi Yapılanlarda Kolorektal Malignite Sıklığı

Akkuzu, Mustafa Zanyar; Sezgın, Orhan; Üçbilek, Enver; Özdoğan, Osman; Aydin, Ferzan; Balci, Hatice; Yaraş, Serkan; Ateş, Fehmi; Altıntaş, Engin

doi:10.17944/mkutfd.790954

Cited by 2 publications

(3 citation statements)

References 22 publications

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“…Quyn et al 20 . reported a 7.1% CRC detection rate in their series of 53,332 cases of FOBT positivity in the screening group, and our findings were similar to several similar studies 12,18 . There are also studies with a lower rate of CRC compared to our study 15,16,19 .…”

Section: Discussionsupporting

confidence: 93%

“…In the study conducted by Levi et al 11 on 16,359 people, of the 2.266 participants undergoing FOBT, 88 (3.9%) tests were positive. In many similar studies, FOBT positivity rates were found to be lower than in our study [12][13][14] . We can attribute the higher rate of FOBT positives in our results, compared to other studies, to the fact that our target group screened with PHE consisted of people aged 50 and over.…”

Section: Discussioncontrasting

confidence: 76%

“…In our study, no pathology was detected with colonoscopy in 21.5% of FOBT positive patients. In other similar studies, 75.7% of patients tested positive for FOBT were reported normal with colonoscopy, which was much higher than in our study 12,15,17 . In other studies similar to our findings, even pathological lesions were not detected in people with FOBT positive 18,19 .…”

Section: Discussioncontrasting

confidence: 62%

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How Effective is a Fecal Occult Blood Test to Detect Malignancy?

ŞAHİN¹,

Güzel²,

METE³

2022

NKTD

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Aim: Cancer, an important public global health problem, is the second leading cause of death after cardiovascular diseases. We aimed to reveal the incidence of colorectal cancer (CRC) by the positive fecal occult blood test (FOBT), requested within the scope of periodic health examination (PHE) in patients applied to the family medicine outpatient clinic. Materials and Methods:A total of 119 people aged between 50 and 70 years, who applied to the family medicine outpatient clinic of a university hospital for general health check-up, were included in the study. A questionnaire, in which socio-demographic data and CRC risk factors were questioned, was applied to the participants. The hemogram, FOBT, colonoscopy, and the pathology results of the patients were evaluated.Results: Of 119 participants, 62 (52.1%) were female and 57 (47.9%) were male. The mean age of the participants was 61.0±7.6 years. FOBT was found to be positive in 65 (54.6%) of all participants. Five people (4.2%) who participated in the study were diagnosed with CRC according to the biopsy results obtained during the colonoscopy procedure. In our study, the rate of malignancy detection in all patients with positive FOBT including CRC diagnosis was found to be 7.7% (n=5). Our study detected statistically significant relationships between FOBT positivity and diagnosis of CRC. Conclusion:Following the appropriate recommendations of PHE guidelines and CRC screenings in individuals with high-risk levels, FOBT contributes to early diagnosis and referral to treatment as soon as possible.

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Section: Discussionsupporting

confidence: 93%

Section: Discussioncontrasting

confidence: 76%

Section: Discussioncontrasting

confidence: 62%

See 1 more Smart Citation

How Effective is a Fecal Occult Blood Test to Detect Malignancy?

ŞAHİN¹,

Güzel²,

METE³

2022

NKTD

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Evaluation of colonoscopic findings in patients undergoing colonoscopy due to positive fecal occult blood test: a single center experience

Düzenli¹,

Kiyak²

2021

Journal of Health Sciences and Medicine

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Aim: Fecal occult blood test is used in the early diagnosis of colorectal cancer. We aimed to evaluate the colonoscopic and pathological findings of patients who underwent colonoscopy due to positive fecal occult blood test in a tertiary center. Material and Method: Patients who had a positive fecal occult blood test and referred to the Health Sciences University, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital endoscopy unit for colonoscopy were included in this study. Age, gender, colonoscopy findings and pathology results of the patients were recorded. Statistical analyzes were performed with SPSS v21.0. Results: Two hundred and twenty three patients were included in the current study. Of the patients, 101 (45.3%) were male and 122 (54.7%) were female, with a mean age of 53.2 (18-90 years). Endoscopic diagnoses were as 49 (22%) polyp, 13 (5.8%) colon cancer, 4 (1.8%) inflammatory bowel disease, 15 (6.7%) diverticulum, 63 (28.3%) perianal disease, 79 (35.4%) normal colonoscopic findings. Pathological features of colon polyps were as; tubular adenoma in 51%, tubulovillous adenoma in 18.4%, serrated adenoma in 2%, and hyperplastic polyp in 28.6%. Colonoscopic findings of patients according to age groups (over and under 50 years of age); the incidence of polyps (p=0.01) and diverticulum (p=0.001) were significantly higher in patients older than 50 years, while perianal diseases (p=0.031) and normal colonoscopic findings (p=0.008) were higher in patients younger than 50 years of age. Conclusion:Colon pathology was detected in approximately 2/3 of the patients presenting with a positive fecal occult blood test. This test is an inexpensive, easily applicable method that helps to detect colon cancer and precursor lesions, as well as pathologies such as subclinical inflammatory bowel disease and diverticulum causing chronic blood loss.

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Gaitada Gizli Kan Pozitifliği Nedeniyle Kolonoskopi Yapılanlarda Kolorektal Malignite Sıklığı

Cited by 2 publications

References 22 publications

How Effective is a Fecal Occult Blood Test to Detect Malignancy?

How Effective is a Fecal Occult Blood Test to Detect Malignancy?

Evaluation of colonoscopic findings in patients undergoing colonoscopy due to positive fecal occult blood test: a single center experience

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