Gallbladder cancer with a low junction of the cystic duct or an anomalous pancreaticobiliary junction

Uetsuji, Shoji; Okuda, Yasuhiro; Ah, Kwon; Komada, Hisanao; Imamura, Atsuro; Takai, Shigeharu; Kamiyama, Yasuo

doi:10.1097/00042737-199612000-00015

Cited by 14 publications

(16 citation statements)

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“…[14][15][16] The gallbladder and the bile duct were the most common sites of double cancer reported in the literature. Also, Uetsuji et al 17 note the significance of a low junction of the cystic duct (LJCD) as another anatomical variation which may have an association with biliary tract neoplasms. They 18 demonstrated, in a retrospective study, that, of 87 patients with gallbladder cancer, 14.9% had LJCD and 12.8% had PBM.…”

Section: Discussionmentioning

confidence: 99%

Double cancer of the cystic duct and gallbladder associated with low junction of the cystic duct

Itoh

Fuji

Taniguchi

et al. 2008

J Hepatobiliary Pancreat Surg

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We report a case of double cancer of the cystic duct and gallbladder associated with low junction of the cystic duct. A 73-year-old woman was admitted to the hospital complaining of upper abdominal pain. Endoscopic retrograde cholangiography showed a stenotic lesion in the lower common bile duct and no visualization of the cystic duct or gallbladder. Enhanced computed tomography revealed a heterogeneously enhanced tumorous lesion around the lower bile duct in the pancreatic head. A diagnosis of cancer arising from the cystic duct that entered the lower part of the common hepatic duct was made by intraductal ultrasonography, which showed an intraluminal protruding lesion in the cystic duct. Isolated gallbladder cancer was also diagnosed, by abdominal computed tomography. She underwent pancreaticoduodenectomy with dissection of regional lymph nodes. Histological examination revealed moderately differentiated adenocarcinoma of the cystic duct and well-differentiated adenocarcinoma of the gallbladder. Double cancer of the cystic duct and gallbladder is extremely rare, and this case also suggests a relationship between a low junction of the cystic duct and neoplasm in the biliary tract.

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Section: Discussionmentioning

confidence: 99%

Double cancer of the cystic duct and gallbladder associated with low junction of the cystic duct

Itoh

Fuji

Taniguchi

et al. 2008

J Hepatobiliary Pancreat Surg

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“…A high incidence of gallbladder carcinoma in patients with APBDJ has been well documented, primarily in Japanese populations. The prevalence of gallbladder carcinoma in patients with APBDJ was 12.5%–64.3%, and the incidence of APBDJ in patients with gallbladder carcinoma was 10.8%–17.2% in several studies 41,42,46,. The highest incidence of APBDJ in patients with gallbladder carcinoma (62.5%) was reported in a Chinese population, and this detection rate is more than three times larger than that in Japanese patients 48.…”

Section: Histopathologic and Clinicopathologic Features Of Premalignamentioning

confidence: 89%

Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings

Sasatomi

Tokunaga

Miyazaki

2000

Journal of Hepato-Biliary-Pancreatic Surgery

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Two distinct epithelial lesions (dysplasia and adenoma) and one high-risk condition (anomalous pancreatico-biliary ductal junction; APBDJ) are currently recognized as premalignant stages of gallbladder carcinogenesis. In addition to clinicopathologic observations, recent molecular genetic studies have provided further insight into the pathogenesis and biological behavior of these precursor lesions. In this review, we concentrate on describing the histopathologic and clinicopathologic background and recent molecular genetic findings for each of these putative precursor lesions.

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“…The incidence of duct anomalies is 13.2%; and the commonest duct anomaly is the long cystic duct fusing low with the common hepatic duct, occurring in 8.6% of cholecystectomies [11,12]. Among these anomalies, a few reports concerned the clinical significance of a low junction of the cystic duct, which may influence the pathophysiology of pancreatobiliary diseases such as gallstone or pancreatitis in patients without AAPBD [4,5].…”

Section: Discussionmentioning

confidence: 99%

“…In patients without AAPBD, low confluence of the cystic duct has been reported to cause pancreatobiliary diseases [4,5]. Although the cystic duct joins the hepatic duct at various points even in patients with AAPBD, there has been no report of clinical significance of the relative position of that junction.…”

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confidence: 99%

Clinical significance of the confluence of the cystic duct in patients with anomalous arrangement of the pancreaticobiliary duct

Fumino

Iwai

Deguchi

et al. 2007

Journal of Pediatric Surgery

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Gallbladder cancer with a low junction of the cystic duct or an anomalous pancreaticobiliary junction

Cited by 14 publications

References 0 publications

Double cancer of the cystic duct and gallbladder associated with low junction of the cystic duct

Double cancer of the cystic duct and gallbladder associated with low junction of the cystic duct

Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings

Clinical significance of the confluence of the cystic duct in patients with anomalous arrangement of the pancreaticobiliary duct

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