2023
DOI: 10.20944/preprints202309.0109.v1
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Galleria mellonella Antimicrobial Peptides and Stress Management Gene Expression in Response to Deleterious Events Caused by Sporothrix brasiliensis

Nathália Faria Reis,
Myrela Conceição Santos De Jesus,
Lais Cavalcanti dos Santos Velasco De Souza
et al.

Abstract: Sporothrix brasiliensis is the most pathogenic species, responsible for the Brazilian cat-transmitted sporotrichosis hyperendemics. In this scenario, investigation of pathogen-host interaction can provide relevant information for future treatment strategies. To this end, the invertebrate Galleria mellonella has proven to be a suitable alternative to evaluate the virulence of pathogenic fungi since the insect immune system is similar to the mammalian innate immune response. The aim of this work was to investiga… Show more

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