“…3 Based on their size and the spatial position of the six cysteine residues, animal defensins are classified as a-, b-, y-defensins of vertebrates (mammalia and birds) and insect defensins. To date, vertebrate defensins were identified in numerous species: mice, [6][7][8] birds-where they are called gallinacins- 9 rats, 10 cattle, 11,12 goats, 13 sheeps, 14 humans, 8,15,16 and non-human primates [17][18][19][20] (reviewed in Martin et al, 4 Hughes, 21 Schroder, 22 and Lehrer and Ganz 23 ). Interestingly, domestic cattle (Bos taurus) was shown to share a broad spectrum of different b-defensins, for example, tap (tracheal antimicrobial peptide), lap (lingual antimicrobial peptide), bnbd (bovine neutrophil peptide), nbd12 (neutrophil beta defensin 12), and ebd (enteric beta defensin).…”