Gambaran Pasien Stroke Pada Lansia di Rumah Sakit Islam Jakarta Sukapura Tahun 2019

Nadhifah, Tiara Amoria; Sjarqiah, Umi

doi:10.24853/mujg.3.1.23-30

Cited by 3 publications

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“…17 Selain itu, penelitian yang dilakukan di Rumah Sakit Islam Jakarta Sukapura pada periode tahun 2019 juga menyatakan bahwa dari 52 sampel kasus stroke mayoritas merupakan kasus stroke nonhemoragik dengan jumlah 49 orang (94%). 18 Adapun penelitian di Rumah Sakit Bethesda Yogyakarta pada periode tahun 2017-2018 ditemukan prevalensi pasien stroke non-hemoragik sebanyak 77% dari total jumlah kasus stroke di periode tersebut. 19 Hal ini didukung dengan patofisiologi stroke non-hemoragik yang terjadi karena adanya gumpalan darah yang menghambat pembuluh darah yang menginervasi otak.…”

Section: Pembahasanunclassified

Relationship Between Hypertension and the Incidence of Stroke in Rsup Prof. Dr. I.G.N.G Ngoerah

Priyatna,

Sinardja,

Sinardja

et al. 2023

eum

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Stroke is a condition that occurs when blood flow to the brain is cut off due to blockage or rupture of blood vessels to the brain, causing brain cell death. Stroke is a disease that has a very high level of morbidity and mortality, especially in Indonesia. Hypertension is one of the main factors of stroke. This study was aimed to determine the relationship of hypertension to the incidence of stroke in RSUP Prof. Dr. I.G.N.G Ngoerah. This study used a cross-sectional analytic observational study design on 150 stroke patients at RSUP Prof. Dr. I.G.N.G Ngoerah in the period June 2021-June 2022. This study shows the proportion of non-hemorrhagic stroke is 56.7% and hemorrhagic stroke is 43.3%; stroke patients who have hypertension by 72.7%; stroke was more common in patients aged ?58 years with a proportion of 52%; and stroke was more common in male patients with a proportion of 63.3%. For the non-parametric correlation value of hypertension with non-hemorrhagic stroke and hemorrhagic stroke found r = 0.265 with p value = 0.001; p<0.05. This value indicates a weak positive relationship between hypertension to the incidence of non-hemorrhagic stroke and hemorrhagic stroke which proved significant. This is due to hypertension causing endothelial dysfunction so that it can trigger the formation of arterosclerosis and/or rupture of blood vessels. Preventive measures to maintain blood pressure play an important role in preventing complications of stroke.

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Section: Pembahasanunclassified

Relationship Between Hypertension and the Incidence of Stroke in Rsup Prof. Dr. I.G.N.G Ngoerah

Priyatna,

Sinardja,

Sinardja

et al. 2023

eum

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“…Usia lansia mengalami kemunduran fungsi termasuk pembuluh darah otak. Pembuluh darah mengalami penurunan elastisitasnya terutama bagian endotel yang akan mengalami penebalan pada bagian intima, sehingga lumen pembuluh darah semakin menyempit dan akan berdampak pada penurunan aliran darah otak (Nadhifah & Sjarqiah, 2022).…”

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Efek suplementasi kombinasi bawang putih, jahe merah, dan beras ragi merah (BJR-22) terhadap kadar kolesterol LDL pasien stroke dengan dislipidemia

Sutoyo,

Aisy,

Rinaldi

et al. 2023

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Background: Stroke is the second leading cause of death worldwide, a significant contributor to disability, and the leading cause of stroke prevention by controlling risk factors. Dyslipidemia is a high risk of plaque buildup in the cell wall. An alternative search must be performed to prevent recurrent stroke events and to improve survival without disability. Nutraceuticals such as garlic (Allium sativum), red ginger (Zingiber officinale Roxb. var. rubrum Rosc.), and red yeast rice (Monascus purpureus) contain active compounds that inhibit HMG-CoA activity and limit the rate of cholesterol synthesis.Objectives: To analyze the effect of red ginger, garlic, and red yeast rice on low-density lipoprotein cholesterol (LDL-C) levels in ischemic stroke patients with dyslipidemia.Methods: Quasi-experimental research was conducted in a double-blinded manner. The study was conducted on outpatients at the Neurology Clinic of Dr. Kariadi Hospital Semarang, Central Java, from September to December 2022. Forty subjects with ischemic stroke and dyslipidemia were divided into intervention (20 subjects) and control (20 subjects) groups using consecutive sampling techniques. The intervention was conducted for 30 days. The intervention group received supplementation with a combination of garlic 225 mg, red ginger 125 mg of red ginger, 250 mg of 3x/day and statin for 30 days, while the control group received a placebo and statin. Lipid profile measurements were conducted at the Central Lab of Dr. Kariadi Hospital, Semarang, India. Data were analyzed using Fisher-Exact, Wilcoxon, and paired t-tests at a 95% CI.Results: The average LDL level before intervention was 152,0 ± 58,54, and after the intervention was 89,0 ± 27,07 (mg/dL). Before the intervention, The intermediate cholesterol level was 207,6 ± 37,6 to 164,5 ± 45,58. There was a significant improvement in LDL-C (p= 0,000) and cholesterol (p= 0,001).Conclusion: Supplementation with a combination of garlic, red ginger, and red yeast rice is effective in reducing LDL cholesterol levels

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Pengaruh Suplementasi Kombinasi Bawang Putih (Allium Sativum), Beras Ragi Merah (Monascus Purpureus), Dan Jahe Merah (Zingiber Officinale Var. Rubrum) Terhadap Kadar Trigliserida Dan HDL Pasien Stroke Iskemik Dengan Dislipidemia

Aisy,

Maharani,

Jaeri

et al. 2024

Journal of Nutrition College

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Background: The incidence of stroke in the world is reported as many as 15 million people each year and around 185 thousand experience recurrent strokes. The incidence of recurrent stroke can be avoided by controlling risk factors, especially dyslipidemia. There is a relationship between dyslipidemia and the risk of atherosclerosis, especially ischemic stroke and peripheral arterial disease. Nutraceuticals can be used as an adjuvant to conventional drugs. Objectives: The purpose of this study was to determine the effect of giving herbs containing garlic (Allium sativum) 675 mg, red yeast rice (Monascus purpureus) 750 mg, and red ginger (zingiber officinale var. rubrum) 375 mg, hereinafter referred to as BJR 22 on TG and HDL levels.Materials and Methods: This research was pre and posttest Control Group Design with double blind method. The research subjects were selected consecutively with 20 intervention groups receiving standard therapy (statins) and BJR 22 3 capsules/day and 20 control groups receiving standard therapy (statins) and placebo once daily, each group being given for 30 days. The data were analyzed used the Shapiro wilk test, Wilcoxon, Chi Square, Fisher's exact and Paired T-test. Results: The average change in TG levels before and after treatment in the intervention group was -5.95 ± 86.88 (p=0.575), while the control group was 4.3 ± 97.08 (p=0.845). There was no significant difference between the two group. The change in HDL levels in the intervention group was 10 ± 13.46, indicating a significant change (p = 0.004). In the control group it was 5.3 ± 27.25 indicating a change that was not significant (p = 0.273). The regression test shows that the factors that influence TG levels are calorie intake and those that influence HDL levels are smoking status, hypertension and fat intake.Conclusion: BJR 22 supplementation of 3 capsules/day for 30 days can improve HDL levels but does not significantly affect triglyceride levels.Keywords: Garlic, Red Yeast Rice, Dyslipidemia, Red Ginger, Stroke ABSTRAKLatar belakang: Penderita stroke memiliki risiko serangan berulang sekitar 11,1 % dalam 1 tahun. Insiden stroke berulang dihindari dengan upaya pengendalian faktor risiko salah satunya dislipidemia. Terdapat hubungan dislipidemia dengan risiko kejadian aterosklerosis terutama penyakit stroke iskemik dan penyakit arteri perifer. Prevalensi penderita statin intoleran ada 9,1%. Nutrasetikal dapat digunakan sebagai terapi adjuvant/pendamping obat konvensional. Tujuan penelitian ini untuk mengetahui efek pemberian herbal yang mengandung bawang putih (Allium sativum) 675 mg, Red Yeast Rice (RYR)/beras ragi merah (Monascus purpureus) 750 mg, dan jahe merah (zingiber officinale var. rubrum) 375 mg yang selanjutnya disebut BJR 22 terhadap kadar trigliserida (TG) dan High Density Lipoprotein (HDL).Metode: Penelitian dengan menggunakan pre and posttest control group design dengan cara double blind. Subjek penelitian dipilih secara konsekutif dengan jumlah 20 orang dalam kelompok intervensi yang mendapatkan terapi standar (statin) dan BJR 22 sebanyak 3 kapsul/hari dan 20 orang dalam kelompok kontrol yang mendapatkan terapi standar (statin) dan plasebo 3x1. Durasi penelitian adalah 30 hari. Data dianalisis menggunakan uji Saphiro Wilk, Wilcoxon, Chi Square, Fisher exact dan Paired T-test.Hasil: Rata-rata perubahan kadar TG sebelum dan sesudah perlakuan di kelompok intervensi adalah -5,95 ± 86,88 mg/dL (p=0,575), sedangkan kelompok kontrol 4,3 ± 97,08 mg/dL (p=0.845) Tidak ada perbedaan signifikan antara kedua kelompok. Perubahan kadar HDL di kelompok intervensi adalah 10 ± 13,46 mg/dL menunjukkan perubahan yang bermakna (p=0,004). Pada kelompok kontrol adalah 5,3 ± 27,25 mg/dL menunjukkan perubahan yang tidak bermakna (p=0,273). Uji regresi menunjukkan faktor yang memengaruhi kadar TG adalah asupan kalori dan yang memengaruhi kadar HDL adalah status merokok, hipertensi dan asupan lemak.Kesimpulan: Suplementasi BJR 22 dosis 3 kapsul/hari dapat memperbaiki kadar HDL namun tidak mempengaruhi kadar trigliserida secara bermakna.Kata Kunci: Bawang putih, Beras Ragi Merah, Dislipidemia, Jahe merah, Stroke

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Gambaran Pasien Stroke Pada Lansia di Rumah Sakit Islam Jakarta Sukapura Tahun 2019

Cited by 3 publications

References 2 publications

Relationship Between Hypertension and the Incidence of Stroke in Rsup Prof. Dr. I.G.N.G Ngoerah

Relationship Between Hypertension and the Incidence of Stroke in Rsup Prof. Dr. I.G.N.G Ngoerah

Efek suplementasi kombinasi bawang putih, jahe merah, dan beras ragi merah (BJR-22) terhadap kadar kolesterol LDL pasien stroke dengan dislipidemia

Pengaruh Suplementasi Kombinasi Bawang Putih (Allium Sativum), Beras Ragi Merah (Monascus Purpureus), Dan Jahe Merah (Zingiber Officinale Var. Rubrum) Terhadap Kadar Trigliserida Dan HDL Pasien Stroke Iskemik Dengan Dislipidemia

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