2006
DOI: 10.1001/archneur.63.2.298-a
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Gambling and Parkinson Disease

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Cited by 89 publications
(72 citation statements)
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“…The disorder may not be specific to any agent but, rather, to the total dopaminergic load. 53 Some have stated that the risk of pathologic gambling is similar for patients taking ropinirole, pergolide and pramipexole, 54 whereas others have argued that the disorder occurs mainly in patients taking pramipexole.…”
mentioning
confidence: 99%
“…The disorder may not be specific to any agent but, rather, to the total dopaminergic load. 53 Some have stated that the risk of pathologic gambling is similar for patients taking ropinirole, pergolide and pramipexole, 54 whereas others have argued that the disorder occurs mainly in patients taking pramipexole.…”
mentioning
confidence: 99%
“…Algunos estudios sugieren un rol importante en el desarrollo de DCI de dosis altas de levodopa (8) , inhibidores de monoamino oxidasa (17) , estimulación cerebral profunda (18) , y los AD como pramipexol (13) , ropinirol y pergolida (8,16) . La prevalencia de hipersexualidad asociada a monoterapia con levodopa es de 0,7% y con un AD puede llegar a 13,7% (5,19) . En un estudio la hipersexualidad, fue más frecuente con pramipexol en relación a otros AD, sin poder establecer una relación clara con la dosis de pramipexol (1) .…”
Section: Discussionunclassified
“…Una serie de casos (16) y publicaciones (21) sugieren una particular asociación de DCI con pramipexol, un AD con especificidad para un receptor de dopamina D3, expresado en gran cantidad en las regiones límbicas (22) ; sin embargo, estudios posteriores no han confirmado esta observación (5,9,19,23) . Los modelos animales de EP con exposición crónica a levodopa, en quienes se desarrolla conductas similares a compulsiones, no demuestran diferencia significativa con los expuestos a pergolida, ropinirol o pramipexol (24) .…”
Section: Discussionunclassified
“…The medication regime becomes increasingly complex as different forms of antiparkinsonian medication are introduced. Side-effects can be disturbing: sudden sleep attacks that can be dangerous for the individual and for other people, for example if driving or handling machinery (Cornella et al 2002), vivid dreams, hallucinations that can occur during the day or night (Arnulf et al 2000), increased libido and compulsive behaviour such as gambling or excessive shopping (Lu et al 2006). .…”
Section: Parkinson's Diseasementioning
confidence: 99%