Gamma Radiation‐Induced Crosslinked PVA/Chitosan Blends for Wound Dressing

Salmawi, Kariman M. El

doi:10.1080/10601320701235891

Cited by 67 publications

(32 citation statements)

References 14 publications

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“…Chitosan has good biocompatibility, biodegradability, and hemostatic properties, the blend of chitosan and PVA by -irradiation can also be used in wound dressing. 81 Silver nanoparticle has antimicrobial capability, which is a highly desirable property in wound dressing materials. NC gels consisting of Ag nanoparticles were found to be excellent materials for antibacterial applications.…”

Section: Application Of Nanocomposite Hydrogelsmentioning

confidence: 99%

Nanocomposite Hydrogels and Their Applications in Drug Delivery and Tissue Engineering

Song¹,

Li²,

Wang³

et al. 2015

j biomed nanotechnol

228

103

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Traditional hydrogels usually possess inferior mechanical properties as well as lacking multi-functionalities. Nano-sized particles/fillers, both inorganic and organic materials, have unique chemical, physical, and biological functions, and have been extensively studied as biomaterials or bio-functional materials. Nanocomposite hydrogels, which combine the advantages of both nano-fillers and hydrogel matrices, may result in improved mechanical and biological properties and find their potential applications in biomedical field. This paper reviews recent developments in the synthesis, preparation, and characterization of nanocomposite hydrogels; their biomedical applications, such as drug delivery matrices and tissue engineering scaffolding materials are also summarized.

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Section: Application Of Nanocomposite Hydrogelsmentioning

confidence: 99%

Nanocomposite Hydrogels and Their Applications in Drug Delivery and Tissue Engineering

Song¹,

Li²,

Wang³

et al. 2015

j biomed nanotechnol

228

103

View full text Add to dashboard Cite

show abstract

“…IPNs have the following two characteristics: firstly, the polymers must be synthesized, or crosslinked, in the presence of the other; secondly, the combination must provide the possibility of effectively producing advanced multicomponent, polymeric systems having new property profiles [3]. Radiation processing using γ-rays, electron beam or X-rays has been demonstrated on a large commercial scale to be a very effective means of improving end use properties of various polymers [4]. It is a well-established and economical method of precisely modifying the properties of bulk polymer resins and formed polymer components [5].…”

Section: Introductionmentioning

confidence: 99%

Radiation induced crosslinking effect on semi - interpenetrating polymer networks of poly(vinyl alcohol)

Mishra¹,

Bajpai²,

Katare³

et al. 2007

Express Polym. Lett.

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Abstract. Semi-IPNs with varying contents of poly(vinyl alcohol) (PVA), poly acrylamide (PAM) and crosslinker N,N'-methylene bis acrylamide (MBA) were prepared by redox polymerization method. The structural and morphological properties were studied by Fourier transform infrared (FTIR) spectroscopy, environmental scanning electron microscopy (ESEM) and X-ray diffraction (XRD) methods, respectively. It was found that the surface of the hydrogel is heterogeneous with separated domains. XRD result shows the semi-crystalline nature of the semi-IPNs. The prepared semi-IPNs of different compositions were subjected to gamma irradiation (2 to 250 kGy) and the radiation induced effects on their strength of the semi-IPNs were studied by measuring the surface microhardness using a Vickers microhardness tester. Significant changes were observed in the Vickers microhardness, which were correlated with molecular architecture of the prepared semi-IPNs.

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“…Studies have shown that the mechanical strength of these hydrogels can be easily further increased with the induction of freeze/thaw cycles to induce different degrees of crystallinity . Crystallinity and thus the hydrogel's mechanical strength can also be increased using common radiation treatments, such as gamma and e‐beam radiation . Furthermore, physical crosslinks and crystallinity can be induced under more mild conditions, including simple aging during storage at room temperature .…”

Section: Introductionmentioning

confidence: 99%

Crystallinity, reversibility, and injectability of physically crosslinked poly(vinyl alcohol) and poly(ethylene glycol) hydrogels

LaMastro

Brewer

Lowman

2019

J of Applied Polymer Sci

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Crystallite regions within a hydrogel network contribute to its mechanical strength, which is crucial for use in load‐bearing applications. However, high amounts of crystallinity can negatively impact the ability for hydrogels to be injected, an attractive property that could replace the need for highly invasive surgical procedures. The reversibility of crystallinity and its lasting impact on the injectability of poly(vinyl alcohol) and poly(ethylene glycol) hydrogels was evaluated in this paper. The relative percent crystallinity in hydrogels was evaluated after storage and autoclaving in syringes in weekly intervals using X‐ray diffraction. Results indicate that crystallinity increased over time and significantly decreased after autoclaving for all samples, where postautoclaved samples contained comparable crystallinity percentages to freshly made gels (p > 0.05). Injectability was evaluated using calculated viscosity. Aged samples were able to be injected after autoclaving, yet there was no determination established between viscosity and storage times based on the data. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48706.

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Gamma Radiation‐Induced Crosslinked PVA/Chitosan Blends for Wound Dressing

Cited by 67 publications

References 14 publications

Nanocomposite Hydrogels and Their Applications in Drug Delivery and Tissue Engineering

Nanocomposite Hydrogels and Their Applications in Drug Delivery and Tissue Engineering

Radiation induced crosslinking effect on semi - interpenetrating polymer networks of poly(vinyl alcohol)

Crystallinity, reversibility, and injectability of physically crosslinked poly(vinyl alcohol) and poly(ethylene glycol) hydrogels

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