Gangliogliomas: clinical, radiological, and histopathological findings in 51 patients.

Zentner, Josef; Wolf, Helmut K.; Ostertun, B.; Hufnagel, A.; Campos, Manuel; Solymosi, L.; Schramm, Johannes

doi:10.1136/jnnp.57.12.1497

Cited by 251 publications

(179 citation statements)

References 27 publications

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“…Even fewer patients show localized ictal onsets on scalp EEG recordings. When seizure patterns are localized, they often are not coextensive with the neoplasm's location (95)(96)(97)(98)(99)(100). Intracranial ictal recordings from surface or deep locations may show localized abnormalities with congruent low voltage fast and theta frequencies superimposed.…”

Section: Localization-related Epilepsymentioning

confidence: 99%

Substrates of Localization‐Related Epilepsies: Biologic Implications of Localizing Findings in Humans

Spencer

1998

Epilepsia

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Section: Localization-related Epilepsymentioning

confidence: 99%

Substrates of Localization‐Related Epilepsies: Biologic Implications of Localizing Findings in Humans

Spencer

1998

Epilepsia

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“…The tumor matrix is often isodense or hyperdense in the pre-contrast CT. Better contrast enhancement can be seen both in the solid tumors and the anaplastic type 3,13,21,22 . Tampier et al 20 preferred to use the term, "cyst-like" to describe the appearance on MRI of a well-defined area with signal intensity similar to CSF on protein density weighted images and higher than CSF on T2WI.…”

Section: Discussionmentioning

confidence: 98%

Ganglioglioma with lytic skull lesions: A case report

et al. 2007

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SummaryGangliogliomas represent only 0.4% of central nervous system neoplasms and 1.3% of brain tumors. They are benign neoplasms with low morbidity and mortality and the patients usually present with seizures, but there has been no adult ganglioglioma with lytic skull lesion.A 49-year-old right handed woman suffering from generalized epileptic seizures was admitted to our hospital. She had also left hemiparesis with 4/5 motor strength. Magnetic resonance imaging and immunohistochemical studies revealed WHO Grade II ganglioglioma. Skull X-ray showed the lytic skull lesions.We have to consider gangliogliomas in the differential diagnosis of lytic skull lesions.KEY WORDS: Ganglioglioma. Lytic skull lesions. Sinaptophysin Ganglioglioma con lesiones líticas en el cráneo: caso clínico ResumenLos gangliocitomas representan sólo el 0'4% de los tumores del sistema nervioso y el 1'3% de los tumores cerebrales. Son tumores benignos con baja mortalidad y morbilidad y los pacientes solían presentarse con crisis comiciales. Nunca se ha presentado un ganglioglioma en el adulto acompañado de lesión lítica craneal.Presentamos el caso de una mujer de 49 años, diestra, que había presentado crisis generalizadas con hemiparesia izquierda. La RM y el estudio histopatológico mostraron un ganglioglioma grado II en la clasificación de la OMS y las Rx de cráneo revelaron lesiones líticas, por lo que consideramos que este tumor debe entrar en la lista del diagnóstico diferencial de las lesiones líticas craneales.

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“…20 Only a small percentage of DNETs are known to calcify. 12 Osteogenic sarcoma and lung and breast carcinomas are the most common primary tumors with brain metastases that calcify.…”

Section: Discussionmentioning

confidence: 99%

“Unusual brain stone”: heavily calcified primary neoplasm with some features suggestive of angiocentric glioma

Sajjad¹,

Kaliaperumal²,

Bermingham

et al. 2015

JNS

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aBBreVIatIoNs DNET = dysembryoplastic neuroepithelial tumor; EMA = epithelial membrane antigen; WHO = World Health Organization. This 40-year-old man presented with a 5-month history of progressive right-sided headache associated with visual blurring. He also had a history of epilepsy but had been seizure free with medication for the past 10 years. An initial CT scan of his brain performed 16 years previously had revealed a small area of calcification in the right parietal region. In the current presentation, he had a left-sided homonymous hemianopia but no other neurological deficits. A CT scan of his brain showed a much larger calcified, partly cystic lesion in the right parietal region. Because he was symptomatic, the lesion was excised and the cyst was drained. Histological examination of the excised tissue showed an unusual primary tumor that was difficult to classify but had some features of angiocentric glioma. The heavy calcification, mixed-density cell population, and regions with features of angiocentric glioma were most unusual. The patient remained asymptomatic 5 years after surgery, and follow-up scans did not show recurrence.

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Gangliogliomas: clinical, radiological, and histopathological findings in 51 patients.

Cited by 251 publications

References 27 publications

Substrates of Localization‐Related Epilepsies: Biologic Implications of Localizing Findings in Humans

Substrates of Localization‐Related Epilepsies: Biologic Implications of Localizing Findings in Humans

Ganglioglioma with lytic skull lesions: A case report

“Unusual brain stone”: heavily calcified primary neoplasm with some features suggestive of angiocentric glioma

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